Agricultural and biological chemistry

Tryptophan production by a lipoic acid auxotroph of Enterobacter aerogenes having both pyruvic acid productivity and high tryptophanase activity

A Yokota, S Oita, S Takao

Index: Yokota, Atsushi; Oita, Shigeru; Takao, Shoichi Agricultural and Biological Chemistry, 1989 , vol. 53, # 8 p. 2037 - 2044

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Citation Number: 13

Abstract

A new process for tryptophan production was established using a lipoic acid auxotrophic mutant, Enterobacter aerogenes l-12, which has both pyruvic acid productivity and tryptophanase activity. The process consists of the production of pyruvic acid from glucose by the washed cells and the subsequent conversion of the acid to tryptophan by the tryptophanase itself in the presence of indole and NH4C1. To prepare washed cells of ...

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