Enzymes in organic syntheses. 19. Evaluation of the stereoselectivities of horse liver alcohol dehydrogenase; catalyzed oxidoreductions of hydroxy-and ketothiolanes, …
JB Jones, HM Schwartz
Index: Jones, J. Bryan; Schwartz, Harold M. Canadian Journal of Chemistry, 1981 , vol. 59, p. 1574 - 1579
Full Text: HTML
Citation Number: 24
Abstract
The specificity of horse liver alcohol dehydrogenase (HLADH) with respect to unsubstituted five-, six-, and seven-membered ring 3-and 4-thiaketone and-thiaalcohol substrates has been examined. The enzyme is found to have a broad tolerance of the structural variations within this series. HLADH also exhibits encouraging (up to 46%) enantiotopic and enantiomeric specificity in preparative-scale reduction and oxidation reactions of the ...
Related Articles:
[Leonard; Figueras Journal of the American Chemical Society, 1952 , vol. 74, p. 917,919]
[Leonard; Figueras Journal of the American Chemical Society, 1952 , vol. 74, p. 917,919]
[Zhou, Taigang; Peters, Byron; Maldonado, Matias F.; Govender, Thavendran; Andersson, Pher G. Journal of the American Chemical Society, 2012 , vol. 134, # 33 p. 13592 - 13595]