Efficient Brønsted Acid Catalyzed Hydrations and Hydroaminations of (Dicyclopropylmethylene) cyclopropane

L Ackermann, SI Kozhushkov, DS Yufit, I Marek

Index: Ackermann, Lutz; Kozhushkov, Sergei I.; Yufit, Dmitry S.; Marek, Ilan Synlett, 2011 , # 11 p. 1515 - 1518

Full Text: HTML

Citation Number: 2

Abstract

Recently we have developed the first intermolecular hydroarylation of highly strained methylenecyclopropanes (MCPs) with conservation of cyclopropane rings via CH bond functionalizations [¹5] through the use of a highly chemoselective ruthenium catalyst. [¹6] However, selected MCPs such as (dicyclopropylmethylene)cyclopropane (1) did not undergo this transformation. Contrarily, attempted hydroarylations employing [RuCl 2 (cod)] n as precatalyst modified with a representative ...