Synthesis

Expedient Synthesis of Perhaloaldehyde N-Acyl Hemiaminals

L Ingrassia, M Mulliez

Index: Ingrassia, Laurent; Mulliez, Michel Synthesis, 1999 , # 10 p. 1731 - 1738

Full Text: HTML

Citation Number: 16

Abstract

Abstract: Various perhaloaldehyde N-acyl hemiaminals 1 are readily prepared in high yields by condensation of amides 7 with easily available perhaloaldehyde O-ethyl hemiacetals 8 or hydrates 9 in the presence of 5 Å molecular sieves. Key words: addition reactions, hemiaminals, fluorine, aldehydes, halides, pseudopeptidic transition state analogs, molecular sieves, perhalogenated aldehyde adducts, side chain peptides

Related Articles:

Synthesis of α-trifluoromethyl-α-hydroxycarboxylate dervatives and their phosphorus-containing analogs with the use of fluorinated diazo compounds

[Titanyuk; Vorob'eva; Osipov; Beletskaya Russian Journal of Organic Chemistry, 2010 , vol. 46, # 5 p. 619 - 623]

N??Acyl??trihalogenacetaldimine als reaktive Zwischenstufen bei Eliminierungs??Additions??Reaktionen, II. Weitere Reaktionen von 2.2. 2??Trifluor??1??äthansulfonyl??N?? …

[Weygand,F. et al. Chemische Berichte, 1966 , vol. 99, p. 1932 - 1943]

More Articles...