CTACl as catalyst for four-component, one-pot synthesis of pyranopyrazole derivatives in aqueous medium

M Wu, Q Feng, D Wan, J Ma

Index: Wu, Mingshu; Feng, Qinqin; Wan, Dehui; Ma, Jinya Synthetic Communications, 2013 , vol. 43, # 12 p. 1721 - 1726

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Citation Number: 26

Abstract

Multicomponent reactions (MCRs) are of increasing importance in organic and medicinal chemistry because the strategies of MCR offer significant advantages over conventional linear syntheses. MCRs leading to interesting heterocyclic scaffolds are particularly useful for the creation of diverse chemical libraries of ''drug-like'' molecules for biological screening, as the combination of three or more low-molecular-weight building blocks in a single operation leads to high ...