Über Heterocyclen, 12. Mitt.: Zur Bromierung der 2-Oxo-6-methyltetrahydropynimidine

G Zigeuner, H Hamberger, H Blaschke…

Index: Zigeuner,G. et al. Monatshefte fuer Chemie, 1966 , vol. 97, p. 1408 - 1421

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Citation Number: 33

Abstract

Abstract Bromine reacts with 6-methyldihydropyrimidine-2-ones or 5-carbethoxy-6- methyldihydropyrimidine-2-ones to yield 6-bromomethyldihydropyrimidine-2-ones. 5- carbethoxy-6-bromomethyldihydropyrimidine-2-ones on heating split off ethyl bromide to give 6-hydroxymethyldihydropyrimidine-2-one-5-carboxylic acid lactones. Chlorine is added to the double bond of 5-carbethoxy-6-methyldihydropyrimidine-2-ones.