Preparation of some functionalized quinoxaline 1, 4??dioxides

JA Usta, MJ Haddadin, CH Issidorides…

Index: Usta, J. A.; Haddadin, M. J.; Issidorides, C. H.; Jarrar, A. A. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 655 - 658

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Citation Number: 5

Abstract

The preparation of some functionalized quinoxaline 1,4-dioxides is described from the reaction of benzo- furazan oxide with 2-acetylbutyrolactone, ethyl acetopyruvate, and acetylacetaldehyde dimethylacetal. ... Previous work in our laboratory has shown that, in the presence of base, benzofurazan oxide (BFO, la) reacts with 2-substituted 1,3-dicarbonyl substrates, such as 2, to give 2,3-dialkylquinoxaline 1,4-dioxides (3, Scheme 1) (1). ... 0 0 0 + CH 3 - C - y H - C - R ~ ak H 3 I1 II