Aminolysis of 2, 2, 2-trichloro-1-arylethanones in aprotic solvents

J Druzian, C Zucco, MC Rezende…

Index: Druzian, Janice; Zucco, Cesar; Rezende, Marcos Caroli; Nome, Faruk Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4767 - 4771

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Citation Number: 20

Abstract

The kinetics of the reaction of the title substrate with various alkylamines was studied in n- heptane, dichloromethane, dioxane, tetrahydrofuran, and acetonitrile. The reaction was third- order in amine when the solvent was n-heptane or dichloromethane. In the other solvents a second-order dependence on [RNH2] was observed. The fourth-order rate constants for the reaction of n-butylamine with various 2, 2, 2-trichloro-l-arylethanones in dichloromethane ...

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