Tetrahedron Letters

One-step synthesis of ketones from car☐ ylic acids and grignard reagents in the presence of a nickel (II)-phosphine catalyst.

V Fiandanese, G Marchese, L Ronzini

Index: Fiandanese, V.; Marchese, G.; Ronzini, L. Tetrahedron Letters, 1983 , vol. 24, # 34 p. 3677 - 3680

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Citation Number: 33

Abstract

Abstract A one-step synthesis of diaryl and alkyl-aryl ketones by the reaction of car☐ ylic acid with Grignard reagents in the presence of NiCl 2 (Ph 2 PCH 2 CH 2 PPh 2) as catalyst is described. In the nickel-catalyzed Grignard reaction the formation of alcohols is nearly ...

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