Terephthalic acid
Suppliers
Names
[ CAS No. ]:
100-21-0
[ Name ]:
Terephthalic acid
[Synonym ]:
TEREPHTHALIC ACID FOR SYNTHESIS
TEREPHTHALIC ACID/BENZENE-1,4-DICARBOXYLIC ACID
benzene-1,4-dicarboxylic acid
p-Phthalic Acid
PURIFIED TEREPHTHALIC ACID
MFCD00002558
Terephthalic acid
EINECS 202-830-0
Terephthalicacid
P-BENZENEDICARBOXYLIC ACID
Caffeic acid
TEREPHTHALIC ACID (TPA)
Chemical & Physical Properties
[ Density]:
1,51 g/cm3
[ Boiling Point ]:
392.4ºC at 760 mmHg
[ Melting Point ]:
300 °C
[ Molecular Formula ]:
C8H6O4
[ Molecular Weight ]:
166.13100
[ Flash Point ]:
260°C
[ Exact Mass ]:
166.02700
[ PSA ]:
74.60000
[ LogP ]:
1.08300
[ Vapour Pressure ]:
1.83E-15mmHg at 25°C
[ Index of Refraction ]:
1.648
[ Storage condition ]:
0-6°C
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WZ0875000
- CHEMICAL NAME :
- Terephthalic acid
- CAS REGISTRY NUMBER :
- 100-21-0
- BEILSTEIN REFERENCE NO. :
- 1909333
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C8-H6-O4
- MOLECULAR WEIGHT :
- 166.14
- WISWESSER LINE NOTATION :
- QVR DVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,317,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1430 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 16,1655,1968
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 767 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,469,1971 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 364 gm/kg/1Y-C
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Liver - changes in liver weight
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570926
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/m3/2H/26W-I
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 7,91,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5964 mg/kg/7D-I
- TOXIC EFFECTS :
- Liver - liver function tests impaired
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 16,1655,1968 *** REVIEWS *** ACGIH TLV-TWA 10 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW BPCT** Progress Report from the Environmental Protection Agency to NIOSH on Benzenepolycarboxylates, 1974 Volume(issue)/page/year: -,183,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82013 No. of Facilities: 1682 (estimated) No. of Industries: 26 No. of Occupations: 42 No. of Employees: 22732 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82013 No. of Facilities: 282 (estimated) No. of Industries: 8 No. of Occupations: 16 No. of Employees: 6456 (estimated) No. of Female Employees: 2563 (estimated)
Safety Information
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
WZ0875000
[ HS Code ]:
2917361100
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2917361100
[ Summary ]:
2917361100 terephthalic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:13.0%。Lowest tariff:6.5%。General tariff:30.0%
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