1-Ethoxy-4-nitrobenzene

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Names

[ CAS No. ]:
100-29-8

[ Name ]:
1-Ethoxy-4-nitrobenzene

[Synonym ]:
4-NITROPHENETOL
1-Ethoxy-4-nitrobenzene
Ethyl p-nitrophenyl ether
4-Nitrophenetole
p-nitroethoxybenzene
EINECS 202-837-9
Ethyl 4-nitrophenyl ether
Benzene, 1-ethoxy-4-nitro-
MFCD00007330
1-Ethoxy-4-nitro-benzene
Phenetole, p-nitro-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
283.0±0.0 °C at 760 mmHg

[ Melting Point ]:
56-60 °C

[ Molecular Formula ]:
C8H9NO3

[ Molecular Weight ]:
167.162

[ Flash Point ]:
134.1±21.8 °C

[ Exact Mass ]:
167.058243

[ PSA ]:
55.05000

[ LogP ]:
2.56

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.535

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DA0600000
CHEMICAL NAME :
Benzene, 1-ethoxy-4-nitro-
CAS REGISTRY NUMBER :
100-29-8
BEILSTEIN REFERENCE NO. :
0972473
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C8-H9-N-O3
MOLECULAR WEIGHT :
167.18
WISWESSER LINE NOTATION :
WNR DO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3300 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>16 gm/kg
TOXIC EFFECTS :
Liver - fatty liver degeneration Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2100 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Lungs, Thorax, or Respiration - respiratory depression Blood - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>7940 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal)

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
5 mg/disc
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 170,11,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4374 No. of Facilities: 6 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 206 (estimated) No. of Female Employees: 23 (estimated)

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25-S22

[ RTECS ]:
DA0600000

[ HS Code ]:
2909309090

Synthetic Route

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%


Related Compounds

  • 2-Bromo-1-ethoxy-4-nitrobenzene
  • 2-Chloro-1-ethoxy-4-nitrobenzene
  • 1-ethoxy-4-fluoro-2-nitrobenzene
  • 1-ethoxy-4,5-diiodo-2-nitrobenzene
  • 1-(ethoxy(methoxy)methyl)-4-nitrobenzene
  • 1-ethoxy-2-iodo-4-nitrobenzene
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-[(3-Methylphenoxy)methyl]pyridine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N-(2-chloro-6-methylphenyl)-2-(phenylamino)thiazole-5-carboxamide
  • tert-Butyl-DL-alanine