Isonicotinonitrile

Names

[ CAS No. ]:
100-48-1

[ Name ]:
Isonicotinonitrile

[Synonym ]:
Isonicotinic acid nitrile
Isonicotinonitrile
4-Pyridinecarbonitrile
4-cyanopyridine
MFCD00006417
Pyridine-4-carbonitrile
EINECS 202-856-2

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
196.3±13.0 °C at 760 mmHg

[ Melting Point ]:
76-79 °C(lit.)

[ Molecular Formula ]:
C₆H₄N₂

[ Molecular Weight ]:
104.109

[ Flash Point ]:
82.7±5.0 °C

[ Exact Mass ]:
104.037445

[ PSA ]:
36.68000

[ LogP ]:
0.41

[ Vapour Pressure ]:
0.4±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.540

[ Stability ]:
Stable. Incompatible with strong bases, strong oxidizing agents, strong acids.

[ Water Solubility ]:
3.2 g/100ml (16.4 ºC)

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S36/37-S24/25

[ RIDADR ]:
3276

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399010

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Pyridinealdoxime
p-Formylpyridine
4-Cyanopyridinium-1-olate
4-Pyridinecarbaldehyde dimethyl hydrazone
Isonicotinamide
4-Picoline
Pyridinium,4-cyano-1-methyl-, iodide (1:1)
Isonicotinaldehyde (Z)-oxime
3-Bromo-4-cyanopyridine
4-picolinylamine

DownStream

Diphenyl(4-pyridyl)methanol
4-cyclooctylpyridine
ETHYL ISONICOTINIMIDATE
3,6-di-4-pyridyl-1,2,4,5-tetrazine
N'-aminopyridine-4-carboximidamide
4-ethvlpvridine
Isoniazid
Isonicotinamide
Phenyl(4-pyridyl)methanol
2-Acetyl-4-cyanopyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Self-assembled hybrid metal oxide base catalysts prepared by simply mixing with organic modifiers.

Nat. Commun. 6 , 8580, (2015)

Multidentate materials formed by simply mixing heterogeneous and homogeneous components are promising for construction of versatile active sites on the surface of heterogeneous compounds, however, to ...

A novel strategy for pharmaceutical cocrystal generation without knowledge of stoichiometric ratio: myricetin cocrystals and a ternary phase diagram.

Pharm. Res. 32(1) , 47-60, (2015)

To develop a streamlined strategy for pharmaceutical cocrystal preparation without knowledge of the stoichiometric ratio by preparing and characterizing the cocrystals of myricetin (MYR) with four coc...