2-Vinylpyridine

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Names

[ CAS No. ]:
100-69-6

[ Name ]:
2-Vinylpyridine

[Synonym ]:
2-Ethenylpyridin
2-Ethenylpyridine
2-Ethenylpryridine
vinyl-pyridine
2-Vinylpyridine
EINECS 202-879-8
Pyridine,2-ethenyl
2VP
T6NJ B1U1
MFCD00006355
α-Vinylpyridine
Pyridine,2-vinyl
2-Pyridylethylene
Pyridine, 2-ethenyl-
2-ethenyl-pyridin
2-vinyl-pyridin
Pyridine, ethenyl-
pyridin-2-ylethylene

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
160.3±9.0 °C at 760 mmHg

[ Melting Point ]:
-50 °C

[ Molecular Formula ]:
C7H7N

[ Molecular Weight ]:
105.137

[ Flash Point ]:
46.7±0.0 °C

[ Exact Mass ]:
105.057846

[ PSA ]:
12.89000

[ LogP ]:
1.34

[ Vapour Pressure ]:
3.1±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.563

[ Stability ]:
Unstable; may be stabilized with a small amount of ter-butyl catechol. Heat sensitive - store cold. Flammable. Incompatible with strong oxidizing agents, strong bases, strong acids.

[ Water Solubility ]:
2.5 g/100 mL (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU1040000
CHEMICAL NAME :
Pyridine, 2-vinyl-
CAS REGISTRY NUMBER :
100-69-6
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C7-H7-N

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,845,1986
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
610 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 57(9-10),64,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
420 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(3),9,1966
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
460 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(3),9,1966
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,845,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
415 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 mg/m3/4H/48W-I
TOXIC EFFECTS :
Behavioral - alteration of classical conditioning Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 10(3),9,1966

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H302-H311-H314-H317-H411

[ Supplemental HS ]:
Corrosive to the respiratory tract.

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R10;R20;R25;R34;R42/43

[ Safety Phrases ]:
S16-S23-S26-S36/37/39-S45-S28A

[ RIDADR ]:
UN 3073 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
UU1040000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Pyridinecarboxaldehyde
  • (Trimethylsilyl)diazomethane
  • 2-picoline
  • 2-(Pyridin-2-yl)ethyl methanesulfonate
  • 2-Pyridineethanamine,N,N-diethyl-
  • Acrylonitrile
  • Acetylene
  • 2-Bromopyridine
  • Vinylmagnesium bromide
  • 2-Pyridine ethanol

DownStream

  • 2-(3-bromo-4,5-dihydro-isoxazol-5-yl)pyridine
  • 2-Cyanoethylpyridine
  • Axitinib
  • 2-(2-nitroethenyl)pyridine
  • 2-(1-benzylpyrrolidin-3-yl)pyridine
  • 2-Bromo-1-pyridin-2-ylethanone
  • 2-Butylpyridine
  • 2-(2-Bromoethyl)pyridine
  • (E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene
  • 2-(2-PYRIDIN-2-YLETHYL)MALONIC ACID

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • 2-Vinylpyridine
  • poly(2-vinylpyridine)
  • 5-Ethyl-2-vinylpyridine
  • 3-NITRO-2-VINYLPYRIDINE
  • 5-NITRO-2-VINYLPYRIDINE
  • 5-cyano-2-vinylpyridine
  • 4-Benzyl-1-[(5-methyl-1-benzofuran-3-yl)acetyl]piperidine
  • N-(1,3-benzodioxol-5-ylmethyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
  • N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(furan-2-ylmethyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
  • N-(furan-2-ylmethyl)-N-(4-methylbenzyl)-2-oxo-2H-chromene-3-carboxamide
  • 2-(4-chloro-3-methylphenoxy)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(2-fluorobenzyl)propanamide
  • 6-bromo-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(2-fluorobenzyl)-3-methyl-1-benzofuran-2-carboxamide
  • 6-bromo-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-methyl-N-[(5-methylfuran-2-yl)methyl]-1-benzofuran-2-carboxamide
  • 1-butyl-4'-hydroxy-1'-(2-methoxyethyl)-3'-[(4-methoxy-3-methylphenyl)carbonyl]spiro[indole-3,2'-pyrrole]-2,5'(1H,1'H)-dione
  • 4-bromo-N-[2-(dimethylamino)-2-(furan-2-yl)ethyl]benzamide
  • N-[2-(dimethylamino)-2-(furan-2-yl)ethyl]-3,5-dimethyl-1-benzofuran-2-carboxamide
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