3,4-Dihydro-2H-pyran-2-carbaldehyde

Suppliers

Names

[ CAS No. ]:
100-73-2

[ Name ]:
3,4-Dihydro-2H-pyran-2-carbaldehyde

[Synonym ]:
3,4-Dihydro-2H-pyran-2-carboxaldehyde
5-Hexenal,2,6-epoxy
Acrolein dimer
2H-Pyran-2-carboxaldehyde, 3,4-dihydro-
2-formyldihydropyran
2-Propenal dimer
3,4-Dihydro-2H-pyran-2-carbaldehyd
3,4-Dihydro-2H-pyran-2-carbaldehyde
EINECS 202-884-5
2H-PYRAN-2-CARBOXALDEHYDE,3,4-DIHYDRO
Pyran aldehyde
2-Formyl-3,4-dihydro-2H-pyran
MFCD00059170

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
185.1±39.0 °C at 760 mmHg

[ Melting Point ]:
-100ºC

[ Molecular Formula ]:
C6H8O2

[ Molecular Weight ]:
112.127

[ Flash Point ]:
73.4±20.6 °C

[ Exact Mass ]:
112.052429

[ PSA ]:
26.30000

[ LogP ]:
-0.17

[ Vapour Pressure ]:
0.7±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.547

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UP6825000
CHEMICAL NAME :
2H-Pyran-2-carboxaldehyde, 3,4-dihydro-
CAS REGISTRY NUMBER :
100-73-2
BEILSTEIN REFERENCE NO. :
0107244
LAST UPDATED :
199806
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C6-H8-O2
MOLECULAR WEIGHT :
112.14
WISWESSER LINE NOTATION :
T6O BUTJ FVH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 7/27/1965 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4920 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3225 ppm/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - respiratory depression Lungs, Thorax, or Respiration - other changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 13,228,1993 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
194 ppm/6H/9D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in platelet count Biochemical - Metabolism (Intermediary) - other proteins
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 36(1,pt2),272,1997

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
16-26-33-36/37/39-45

[ RIDADR ]:
UN 2607

[ RTECS ]:
UP6825000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

Synthetic Route

Precursor & DownStream

Precursor

  • acrolein
  • 3,4-dihydro-2H-pyran-2-ylmethanol
  • acrylic acid methyl ester
  • 3,4-dihydro-2H-pyran-2-ylmethyl 3,4-dihydro-2H-pyran-2-carboxylate
  • Methyl vinyl ketone
  • N-Butyl Vinyl Ether

DownStream

  • UNII:9BYT763GMT
  • 3,4-dihydro-2H-pyran-2-ylmethanol
  • oxane-2-carbaldehyde
  • 2H-Pyran-2-methanol,3,4-dihydro-, 2-acetate
  • Glutaric acid
  • 1-Hexanol
  • Hexan-1,6-diol
  • 6,8-Dioxabicyclo[3.2.1]octane
  • opt.-inakt.7-Aethyl-6,8-dioxa-bicyclo[3,2,1]octan

Related Compounds

  • 6-methyl-3,4-dihydro-2H-pyran-2-carbaldehyde
  • 2-methyl-3,4-dihydro-2H-pyran-2-carbaldehyde
  • 2,5-Diethyl-3,4-dihydro-2H-pyran-2-carbaldehyde
  • 2,5-diethoxy-3,4-dihydro-2H-pyran-2-carbaldehyde
  • 2,6-Dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde
  • 2,5-dipropyl-3,4-dihydro-2H-pyran-2-carbaldehyde
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine