Solketal
Suppliers
Names
[ CAS No. ]:
100-79-8
[ Name ]:
Solketal
[Synonym ]:
(±)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
Solketal
(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol
2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxacyclopentane
2,3-(Isopropylidenedioxy)propanol
(±)-2,2-Dimethyl-1,3-dioxolane-4-methanol
1,2-Isopropylidene-rac-glycerol
(RS)-Solketal
2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
1,2-Isopropylideneglycerol
T5O COTJ B1 B1 D1Q
1,2-O-Isopropylideneglycerol
(±)-1,2-O-Isopropylideneglycerol
(±)-2,3-O-Isopropylideneglycerol
EINECS 202-888-7
2,3-O-Isopropylideneglycerol
DL-1,2-O-Isopropylidene glycerol
1,3-Dioxolane-4-methanol, 2,2-dimethyl-
α,β-Isopropylideneglycerol
Glycerol acetonide
2,3-Isopropylideneglycerol
MFCD00063238
2,2-Dimethyl-1,3-dioxolane-4-methanol
Isopropylidene glycerol
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
188.5±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H12O3
[ Molecular Weight ]:
132.158
[ Flash Point ]:
80.0±0.0 °C
[ Exact Mass ]:
132.078644
[ PSA ]:
38.69000
[ LogP ]:
0.06
[ Vapour Pressure ]:
0.2±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.424
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
miscible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JI0400000
- CHEMICAL NAME :
- 1,3-Dioxolane-4-methanol, 2,2-dimethyl-
- CAS REGISTRY NUMBER :
- 100-79-8
- BEILSTEIN REFERENCE NO. :
- 0104465
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C6-H12-O3
- MOLECULAR WEIGHT :
- 132.18
- WISWESSER LINE NOTATION :
- T5O COTJ B1 B1 D1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3740 ug/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP elevation not characterized in autonomic section Vascular - BP lowering not characterized in autonomic section
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 8530 ug/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP elevation not characterized in autonomic section Vascular - BP lowering not characterized in autonomic section
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 21,349,1984
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S24/25
[ WGK Germany ]:
2
[ RTECS ]:
JI0400000
[ HS Code ]:
29329970
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2932999099
[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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