Mephentermine

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Names

[ CAS No. ]:
100-92-5

[ Name ]:
Mephentermine

[Synonym ]:
Wyfentermina
Mephine
(1,1-dimethyl-2-phenyl-ethyl)-methyl-amine
Mefentermin
Mephenterdrine
Wyamine
Mephenterdrinum
Mephentermine
Mefenterdrin
N-Methyl-N-(1,1-dimethyl-phenaethyl)-amin
Vialin
2-Methylamino-2-methyl-1-phenyl-propan
(1,1-Dimethyl-2-phenyl-aethyl)-methyl-amin
Mephetedrine
EINECS 202-901-6

Chemical & Physical Properties

[ Density]:
0.903g/cm3

[ Boiling Point ]:
229.4ºC at 760mmHg

[ Molecular Formula ]:
C11H17N

[ Molecular Weight ]:
163.25900

[ Flash Point ]:
90ºC

[ Exact Mass ]:
163.13600

[ PSA ]:
12.03000

[ LogP ]:
2.61800

[ Vapour Pressure ]:
0.0697mmHg at 25°C

[ Index of Refraction ]:
1.501

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SI3675000
CHEMICAL NAME :
Phenethylamine, N,alpha,alpha-trimethyl-
CAS REGISTRY NUMBER :
100-92-5
BEILSTEIN REFERENCE NO. :
1363850
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C11-H17-N
MOLECULAR WEIGHT :
163.29
WISWESSER LINE NOTATION :
1MX1&1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
85 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - excitement
REFERENCE :
ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 111,169,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - excitement
REFERENCE :
ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 111,169,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
57 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - excitement
REFERENCE :
ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 111,169,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
89 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - excitement
REFERENCE :
ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 111,169,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
43 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - excitement
REFERENCE :
ZPPLBF Zentralblatt fuer Pharmazie, Pharmakotherapie und Laboratoriums-diagnostik. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, 102 Berlin, Ger. Dem. Rep.) V.109- 1970- Volume(issue)/page/year: 111,169,1972

Safety Information

[ HS Code ]:
2921499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzenemethanol, a-(1-amino-1-methylethyl)-
  • Phentermine
  • benzylidene-(1,1-dimethyl-2-phenyl-ethyl)-amine
  • methyl iodide
  • Benzylmagnesium chloride
  • 2-Methyl-1-phenyl-2-propanol
  • Sodium cyanide

DownStream

  • Oxethazaine
  • 1-cyclohexyl-N,2-dimethylpropan-2-amine
  • N-methyl-N-(2-methyl-1-phenylpropan-2-yl)hydroxylamine

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • Mephentermine sulfate
  • Mephentermine Hydrochloride
  • Mephentermine sulfate dihydrate
  • 2-Fluoro-3-iodo-1-methoxy-4-(methoxymethoxy)benzene
  • 3-Fluoro-2-iodo-4-methoxyphenol
  • [(5-cyclopropyl-1-pentyl-1H-1,2,3-triazol-4-yl)methyl](methyl)amine
  • 1-(Benzyloxy)-4-bromo-5-chloro-2-methoxybenzene
  • (5-Chloro-3-ethoxy-2-fluorophenyl)methanol
  • 4-Bromo-2-fluoro-1-((4-methoxybenzyl)oxy)benzene
  • 1,5-Dibromo-2-iodo-4-(trifluoromethoxy)benzene
  • 1,2,4-Tribromo-5-(trifluoromethoxy)benzene
  • 1-[(2-bromophenyl)methyl]-5-ethyl-1H-1,2,3-triazole-4-carbothioamide
  • 1-Bromo-4-(t-butyl)-2-isopropoxybenZene
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