BMS-754807

Suppliers

Names

[ Name ]:
BMS-754807

[Synonym ]:
(2S)-1-[4-[(5-Cyclopropyl-1h-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridyl)-2-methyl-pyrrolidine-2-carboxamide
BMS-754807
1-{4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoro-3-pyridinyl)-2-methyl-L-prolinamide
2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-, (2S)-
cc-531
BMS754807

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₂₃H₂₄FN₉O

[ Molecular Weight ]:
461.495

[ Exact Mass ]:
461.208771

[ PSA ]:
116.13000

[ LogP ]:
1.76

[ Index of Refraction ]:
1.795

[ Storage condition ]:
-20℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.

Mol. Cancer Ther. 8(12) , 3341-9, (2009)

BMS-754807 is a potent and reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases (Ki, <2 nmol/L). It is currently in phase I development for the treatment o...

BMS-754807
BMS-P5
BMS-8
BMS-538203
BMS-794833
BMS-779788
4-(Difluoromethyl)-3-fluoropyridine-2,5-diol
3-(4-(Difluoromethyl)-2-ethylphenyl)propanenitrile
4-Bromo-6-(difluoromethyl)-5-methylpyridine-3-sulfonyl chloride
(4-Amino-2-(difluoromethyl)-6-methylpyridin-3-yl)methanol
4-(Difluoromethyl)-6-(hydroxymethyl)pyridine-2,3-diol
4-(Difluoromethyl)-2,5-dihydroxypyridine-3-sulfonamide
4-(Difluoromethyl)-6-fluoro-5-methoxynicotinamide
4-Bromo-2-(difluoromethyl)-5-methyl-3-nitropyridine
4-(Difluoromethyl)-2,6-dimethoxynicotinic acid
N,N-Dimethyl-1-(4-(2,3,4-trichlorophenyl)-1H-indol-3-yl)methanamine

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