BMS-754807

Suppliers

Names

[ Name ]:
BMS-754807

[Synonym ]:
(2S)-1-[4-[(5-Cyclopropyl-1h-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridyl)-2-methyl-pyrrolidine-2-carboxamide
BMS-754807
1-{4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoro-3-pyridinyl)-2-methyl-L-prolinamide
2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-, (2S)-
cc-531
BMS754807

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C₂₃H₂₄FN₉O

[ Molecular Weight ]:
461.495

[ Exact Mass ]:
461.208771

[ PSA ]:
116.13000

[ LogP ]:
1.76

[ Index of Refraction ]:
1.795

[ Storage condition ]:
-20℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.

Mol. Cancer Ther. 8(12) , 3341-9, (2009)

BMS-754807 is a potent and reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases (Ki, <2 nmol/L). It is currently in phase I development for the treatment o...