BMS-754807

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Names

[ CAS No. ]:
1001350-96-4

[ Name ]:
BMS-754807

[Synonym ]:
(2S)-1-[4-[(5-Cyclopropyl-1h-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridyl)-2-methyl-pyrrolidine-2-carboxamide
BMS-754807
1-{4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoro-3-pyridinyl)-2-methyl-L-prolinamide
2-Pyrrolidinecarboxamide, 1-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-, (2S)-
cc-531
BMS754807

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C23H24FN9O

[ Molecular Weight ]:
461.495

[ Exact Mass ]:
461.208771

[ PSA ]:
116.13000

[ LogP ]:
1.76

[ Index of Refraction ]:
1.795

[ Storage condition ]:
-20℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.

Mol. Cancer Ther. 8(12) , 3341-9, (2009)

BMS-754807 is a potent and reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases (Ki, <2 nmol/L). It is currently in phase I development for the treatment o...


More Articles

Related Compounds

  • BMS-754807
  • BMS-P5
  • BMS-8
  • BMS-538203
  • BMS-794833
  • BMS-779788
  • 6-Fluoro-1-methyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
  • 1,4,8-Trimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
  • 6-(3-Methoxybenzyl)-5-oxothiomorpholine-3-carboxylic acid
  • 1,8-Dimethyl-2-oxo-1,2-dihydroquinoline-4-carboxylic acid
  • 7-Fluoro-1,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
  • 8-Chloro-1,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
  • 8-Fluoro-1,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
  • 6-(3-Fluorobenzyl)-5-oxothiomorpholine-3-carboxylic acid
  • 3-Thiomorpholinecarboxylic acid, 6-[(3-chloro-4-methylphenyl)methyl]-5-oxo-
  • 6,7-Difluoro-1,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid
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