1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one

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Names

[ CAS No. ]:
10045-45-1

[ Name ]:
1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one

[Synonym ]:
2H-Benzimidazol-2-one, 1-ethyl-1,3-dihydro-
EINECS 233-148-1
1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one

Chemical & Physical Properties

[ Density]:
1.161±0.06 g/cm3

[ Melting Point ]:
122 ºC

[ Molecular Formula ]:
C9H10N2O

[ Molecular Weight ]:
162.189

[ Exact Mass ]:
162.079315

[ PSA ]:
37.79000

[ LogP ]:
1.39

[ Appearance of Characters ]:
powder

[ Index of Refraction ]:
1.566

[ Storage condition ]:
Store at RT

[ Water Solubility ]:
Slightly soluble (1.6 g/L) (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N1-Ethylbenzene-1,2-diamine
  • N,N-Carbonyldiimidazole
  • 2-ethylaminobenzamide
  • 1-ethyl-3-(1-phenylvinyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
  • 1-(2-bromophenyl)-1-(ethyl)urea
  • o-(Ethylamino)benzohydroxamsaeure
  • 1-ethyl-3-hex-1-enylbenzimidazol-2-one
  • Benzoyl azide, 2-(ethylamino)
  • n-ethyl-2-nitroaniline
  • 2H-Benzimidazole-2-thione,1-ethyl-1,3-dihydro-(9CI)

DownStream

  • 1-ethyl-3-hex-1-enylbenzimidazol-2-one

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Differentiation between human ClC-2 and CFTR Cl- channels with pharmacological agents.

Am. J. Physiol. Cell Physiol. 307(5) , C479-92, (2014)

It has been difficult to separate/identify the roles of ClC-2 and CFTR in Cl(-) transport studies. Using pharmacological agents, we aimed to differentiate functionally between ClC-2 and CFTR Cl(-) cha...

Type 2 diabetes: increased expression and contribution of IKCa channels to vasodilation in small mesenteric arteries of ZDF rats.

Am. J. Physiol. Heart Circ. Physiol. 307(8) , H1093-102, (2014)

Impaired endothelial function, which is dysregulated in diabetes, also precedes hypertension. We hypothesized that in Type 2 diabetes, the impaired endothelium-dependent relaxation is due to a loss of...

Firing pattern modulation through SK channel current increase underlies neuronal survival in an organotypic slice model of Parkinson's disease.

Mol. Neurobiol. 51(1) , 424-36, (2015)

Dopaminergic (DA) neurons in substantia nigra pars compacta (SNc) are vulnerable to excitotoxicity in Parkinson's disease (PD). Neurotoxic stimuli may alter the firing patterns of DA neurons. However,...


More Articles

Related Compounds

  • 6-Chloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one
  • 5-Chloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one
  • 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one
  • 1-[2-(4-morpholinyl)ethyl]-1,3-dihydro-2H-benzimidazol-2-one
  • 4-(1-ethyl-1-hydroxypropyl)-1,3-dihydro-2H-benzimidazol-2-one
  • 2H-Benzimidazol-2-one,1-ethyl-1,3-dihydro-6-hydroxy-(9CI)