Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat

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Names

[ CAS No. ]:
100490-99-1

[ Name ]:
Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat

Chemical & Physical Properties

[ Density]:
1.510

[ Melting Point ]:
138-139℃

[ Molecular Formula ]:
C17H11Cl2F3N2O3

[ Molecular Weight ]:
419.18200

[ Exact Mass ]:
418.01000

[ PSA ]:
68.29000

[ LogP ]:
4.62050

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,4-Difluoroaniline
  • Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate
  • Triethyl orthoformate
  • 2,6-dichloro-5-fluoronicotinoyl chloride
  • 2,6-Dichloro-5-fluoronicotinic acid
  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate

DownStream

  • Tosufloxacin pharmaceutical intermediate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylate
  • ETHYL 1-(2,4-DIFLUOROPHENYL)-7-CHORO-6-FLUORO-4-OXO-HYDROPYRIDINO[2,3-B] PYRIDINE-3-CARBOXYLATE

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-(Bromodifluoromethyl)benzonitrile
  • 4-cyclopropyl-N-(3-(dimethylamino)propyl)-N-methyl-2-nitrobenzenamine
  • 3-[2-(2-aminopyrimidin-5-yl)ethynyl]-N-[3-(trifluoromethyl)phenyl]benzamide
  • Ethyl 3-[(2-ethoxy-2-oxoethyl)amino]-4,4,5,5,6,6,7,7,7-nonafluoroheptanoate
  • 1-(2-amino-4-(trifluoromethyl)phenyl)-N,N-dimethylpiperidin-4-amine
  • (S)-tert-butyl 1-(2-(2-fluoro-5-iodobenzamido)-4-(trifluoromethyl)phenyl)piperidin-3-yl(methyl)carbamate
  • Ethyl 4-(4-(cyclohexylmethyl)-4-hydroxypiperidin-1-yl)benzoate
  • Methyl 2-amino-5-acetamidobenzoate
  • Ethyl 4-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)benzoate
  • 4-[(2-Methyl-1-phenylsulfanylpropan-2-yl)amino]-3-nitrobenzenesulfonamide
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