Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat

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Names

[ CAS No. ]:
100490-99-1

[ Name ]:
Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat

Chemical & Physical Properties

[ Density]:
1.510

[ Melting Point ]:
138-139℃

[ Molecular Formula ]:
C17H11Cl2F3N2O3

[ Molecular Weight ]:
419.18200

[ Exact Mass ]:
418.01000

[ PSA ]:
68.29000

[ LogP ]:
4.62050

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,4-Difluoroaniline
  • Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate
  • Triethyl orthoformate
  • 2,6-dichloro-5-fluoronicotinoyl chloride
  • 2,6-Dichloro-5-fluoronicotinic acid
  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate

DownStream

  • Tosufloxacin pharmaceutical intermediate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylate
  • ETHYL 1-(2,4-DIFLUOROPHENYL)-7-CHORO-6-FLUORO-4-OXO-HYDROPYRIDINO[2,3-B] PYRIDINE-3-CARBOXYLATE

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2,4-Dichloro-5-(difluoromethoxy)benzenethiol
  • 2-(2-Chloro-5-(difluoromethyl)-4-nitropyridin-3-yl)acetic acid
  • 5-Chloro-4-(difluoromethyl)-3-methylpyridin-2-amine
  • 2-(2-Chloro-6-(difluoromethyl)-5-(trifluoromethyl)pyridin-3-yl)acetic acid
  • 2-(2-Cyano-3-(difluoromethoxy)-4-fluorophenyl)acetic acid
  • 2-Cyano-4-(difluoromethyl)-5-formylbenzoic acid
  • 2-(2-Cyano-3-(difluoromethyl)-5-nitrophenyl)acetic acid
  • 3-(Difluoromethyl)-2,6-bis(trifluoromethyl)benzaldehyde
  • 2-Cyano-3-(difluoromethoxy)-5-(hydroxymethyl)benzoic acid
  • 3-(Difluoromethyl)-4-(trifluoromethoxy)pyridin-2-amine