ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,8-naphthyridine-3-carboxylate

Names

[ CAS No. ]:
100491-30-3

[ Name ]:
ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,8-naphthyridine-3-carboxylate

[Synonym ]:
ethyl 7-chloro-1-(4-fluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 1-p-fluorophenyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

Chemical & Physical Properties

[ Molecular Formula ]:
C17H11ClF2N2O3

[ Molecular Weight ]:
364.73100

[ Exact Mass ]:
364.04300

[ PSA ]:
61.19000

[ LogP ]:
3.49400

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ethyl 3-p-fluoroanilino-2-(2,6-dichloro-5-fluoronicotinyl)acrylate
  • Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate
  • 4-Fluoroaniline
  • 2,6-dichloro-5-fluoronicotinoyl chloride
  • 2,6-Dichloro-5-fluoronicotinic acid
  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate

DownStream

  • ethyl 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
  • ethyl 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylate