ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate

Names

[ CAS No. ]:
100491-63-2

[ Name ]:
ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate

[Synonym ]:
ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

Chemical & Physical Properties

[ Molecular Formula ]:
C22H21F3N4O3

[ Molecular Weight ]:
446.42200

[ Exact Mass ]:
446.15700

[ PSA ]:
76.46000

[ LogP ]:
3.17160

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Methylpiperazine
  • ETHYL 1-(2,4-DIFLUOROPHENYL)-7-CHORO-6-FLUORO-4-OXO-HYDROPYRIDINO[2,3-B] PYRIDINE-3-CARBOXYLATE
  • Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate
  • 2,6-dichloro-5-fluoronicotinoyl chloride
  • 2,6-Dichloro-5-fluoronicotinic acid
  • ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate
  • Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat

DownStream