ISPA-28

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Names

[ CAS No. ]:
1006335-39-2

[ Name ]:
ISPA-28

[Synonym ]:
5-Isoxazolecarboxamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-1,2-oxazole-5-carboxamide
MFCD08106635

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C21H24N6O3

[ Molecular Weight ]:
408.454

[ Exact Mass ]:
408.190979

[ LogP ]:
0.18

[ Index of Refraction ]:
1.672

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake.

J. Biol. Chem. 288(27) , 19429-40, (2013)

Acquired antimalarial drug resistance produces treatment failures and has led to periods of global disease resurgence. In Plasmodium falciparum, resistance is known to arise through genome-level chang...

Malaria parasite mutants with altered erythrocyte permeability: a new drug resistance mechanism and important molecular tool.

Future Microbiol. 5(1) , 81-97, (2010)

Erythrocytes infected with plasmodia, including those that cause human malaria, have increased permeability to a diverse collection of organic and inorganic solutes. While these increases have been kn...


More Articles


Related Compounds

  • sodium,3-[2-[[3-carbamoyloxy-2-[[2-(2,3-dihydroxypropanoylamino)acetyl]-methylamino]propanoyl]amino]propanoylamino]-2-oxoazetidine-1-sulfonate
  • (24ξ)-28-[[2-O-(2-O,4-O-Dimethyl-β-D-xylopyranosyl)-α-L-arabinofuranosyl]oxy]-5α-ergostane-3β,4β,6α,8,15β,16β-hexaol
  • COR 28 10
  • COR 28 22
  • 18,28-Cyclo-16,28-secosolanid-5-en-3β-ol
  • (24ξ)-28-[[2-O-(2-O,4-O-Dimethyl-β-D-xylopyranosyl)-α-L-arabinofuranosyl]oxy]-5α-ergostane-3β,6α,8,15β,16β-pentaol
  • Methyl(1R)-2,2-dimethyl-4-oxocyclohexane-1-carboxylate
  • tert-Butyl ((2-methylpyridin-4-yl)methyl)carbamate
  • 1-Bromo-2-[(3-chloro-2-propyn-1-yl)oxy]benzene
  • 4,5,6,7-tetrahydro-1H-indol-2-ol
  • Benzyl 4-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-2-cyanopiperidine-1-carboxylate
  • 1-[3-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]cyclopropanecarboxylic acid methyl ester
  • (E)-3-(2-iodophenyl)prop-2-en-1-ol
  • (1R)-2-amino-1-(6-chloropyridin-3-yl)ethan-1-ol
  • 3-Amino-1-(4-methoxypyridin-2-yl)propan-1-one
  • (1R)-1-(1H-1,3-benzodiazol-5-yl)ethan-1-ol
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