ISPA-28

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Names

[ CAS No. ]:
1006335-39-2

[ Name ]:
ISPA-28

[Synonym ]:
5-Isoxazolecarboxamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-4,5-dihydro-1,2-oxazole-5-carboxamide
MFCD08106635

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C21H24N6O3

[ Molecular Weight ]:
408.454

[ Exact Mass ]:
408.190979

[ LogP ]:
0.18

[ Index of Refraction ]:
1.672

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

An epigenetic antimalarial resistance mechanism involving parasite genes linked to nutrient uptake.

J. Biol. Chem. 288(27) , 19429-40, (2013)

Acquired antimalarial drug resistance produces treatment failures and has led to periods of global disease resurgence. In Plasmodium falciparum, resistance is known to arise through genome-level chang...

Malaria parasite mutants with altered erythrocyte permeability: a new drug resistance mechanism and important molecular tool.

Future Microbiol. 5(1) , 81-97, (2010)

Erythrocytes infected with plasmodia, including those that cause human malaria, have increased permeability to a diverse collection of organic and inorganic solutes. While these increases have been kn...


More Articles


Related Compounds

  • sodium,3-[2-[[3-carbamoyloxy-2-[[2-(2,3-dihydroxypropanoylamino)acetyl]-methylamino]propanoyl]amino]propanoylamino]-2-oxoazetidine-1-sulfonate
  • (24ξ)-28-[[2-O-(2-O,4-O-Dimethyl-β-D-xylopyranosyl)-α-L-arabinofuranosyl]oxy]-5α-ergostane-3β,4β,6α,8,15β,16β-hexaol
  • COR 28 10
  • COR 28 22
  • 18,28-Cyclo-16,28-secosolanid-5-en-3β-ol
  • (24ξ)-28-[[2-O-(2-O,4-O-Dimethyl-β-D-xylopyranosyl)-α-L-arabinofuranosyl]oxy]-5α-ergostane-3β,6α,8,15β,16β-pentaol
  • 2-(ethylsulfonyl)-1-(2-methylbenzyl)-1H-benzo[d]imidazole
  • 1,2 Dimethoxybutane
  • 1-(2,6-dimethylmorpholino)-2-(2-(ethylsulfonyl)-1H-benzo[d]imidazol-1-yl)ethanone
  • (5-ethoxy-1,3-oxathiolan-2-yl)methyl Benzoate
  • 1-(2-(Trimethylsilyl)ethoxymethyl)-4-(4-fluorophenyl)-5-(4-pyridyl)imidazole
  • 3-Chloro-2-(2,2,6,6-tetramethylpiperidin-4-yloxy)pyridine
  • ethyl 4-(3-t-butyl-5-amino-1H-pyrazol-1-yl)benzoate
  • 7-Methoxy-2-phenyl-3-p-tolylchromen-4-one
  • 1-[(4-Aminophenyl)methyl]piperidine-2,6-dione
  • 1-Chloro-4-fluorophthalazine
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