2-chloroethyl-[2-[(6-chloro-2-methoxyacridin-9-yl)azaniumyl]ethyl]azanium,dichloride

Names

[ CAS No. ]:
10072-24-9

[ Name ]:
2-chloroethyl-[2-[(6-chloro-2-methoxyacridin-9-yl)azaniumyl]ethyl]azanium,dichloride

[Synonym ]:
9-(2-((2-Chloroethyl)amino)ethylamino)-6-chloro-2-methoxyacridine,dihydrochloride
ICR 171
ICR-125
Acridine,9-(2-((2-chloroethyl)amino)ethylamino)-6-chloro-2-methoxy-,dihydrochloride
Quinacrine ethyl M/2
2-chloroethyl-[2-[(6-chloro-2-methoxyacridin-9-yl)azaniumyl]ethyl]azanium dichloride

Chemical & Physical Properties

[ Boiling Point ]:
566.8ºC at 760mmHg

[ Molecular Formula ]:
C18H21Cl4N3O

[ Molecular Weight ]:
437.19100

[ Flash Point ]:
296.6ºC

[ Exact Mass ]:
435.04400

[ PSA ]:
49.41000

[ LogP ]:
5.70710

[ Vapour Pressure ]:
7.23E-13mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR8050000
CHEMICAL NAME :
Acridine, 9-(2-((2-chloroethyl)amino)ethylamino)-6-chloro-2-met hoxy-, dihydrochloride, hydrate
CAS REGISTRY NUMBER :
10072-24-9
LAST UPDATED :
199304
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H19-Cl2-N3-O.2Cl-H.H2-O
MOLECULAR WEIGHT :
454.23
WISWESSER LINE NOTATION :
T C666 BNJ EG IM2M2G LO1 &GH 2 &QH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
570 mg/kg/4W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 36,915,1966

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1-benzyl-8-(3,5-dimethyl-1H-pyrazol-1-yl)-7-ethyl-3-methyl-1H-purine-2,6(3H,7H)-dione
  • 2-(2-(hydroxymethyl)-5-methoxy-4-oxopyridin-1(4H)-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
  • 4-ethyl-3-(3-methoxy-1-methyl-1H-pyrazol-4-yl)-5-(methylthio)-4H-1,2,4-triazole
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde