5-Bromoindole

Suppliers

Names

[ Name ]:
5-Bromoindole

[Synonym ]:
5-Br-indole
5-Bromo-1H-indole
5-bromo-indole
EINECS 233-208-7
5-BI
5-broMo-2H-indole
1H-Indole, 5-bromo-
5-bromonindole
5-Bromide indole
5-indolyl bromide
MFCD00005670
5-Bromindole
5-Bromoindole
Bromoindole
5-BROMO INDOLE

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
316.9±15.0 °C at 760 mmHg

[ Melting Point ]:
90-92 °C(lit.)

[ Molecular Formula ]:
C₈H₆BrN

[ Molecular Weight ]:
196.044

[ Flash Point ]:
145.5±20.4 °C

[ Exact Mass ]:
194.968353

[ PSA ]:
15.79000

[ LogP ]:
3.00

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.712

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29339990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

SODIUM 1-ACETYLINDOLINE-2-SULFONATE
5-Bromoindole-3-carboxaldehyde
TERT-BUTYL 5-BROMO-1H-INDOLE-1-CARBOXYLATE
1H-Indol-5-yl trifluoromethanesulfonate
[(E)-2-(5-bromo-2-nitro-phenyl)-vinyl]-dimethyl-amine
5-Bromo-1-(phenylsulfonyl)-1H-indole
5-bromo-1-methylsulfonylindole
5-Bromoindoline
1H-Indole-1-carboxylic acid, 5-bromo-2,3-dihydro-, methyl ester

DownStream

Dimethyltryptamine
2-(5-Bromo-1H-indol-3-yl)ethanol
5-Bromo-1-methyl-1H-indole-3-carboxylic acid
5-Bromo-N-Boc-indol-2-boronic acid
Ethyl 1H-indole-5-carboxylate
1H-Indole, 5-(tributylstannyl)-
5-(4-FLUORO-PHENYL)-1H-INDOLE
5-Chloroindole
5-Bromo-1H-indole-3-carbonitrile
2-(5-Bromo-1H-indol-3-yl)acetic acid

Customs

[ HS Code ]: 29339990

Articles

Identification of novel CYP2A6 inhibitors by virtual screening

Bioorg. Med. Chem. 19 , 7186-93, (2011)

The human CYP2A6 enzyme metabolises several xenobiotics including nicotine, the addictive component in tobacco. Reduced activity of CYP2A6, either for genetic reasons or by administering inhibitors of...

Rational design of novel CYP2A6 inhibitors.

Bioorg. Med. Chem. 22(23) , 6655-64, (2015)

Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by e...

Untargeted Screening and Distribution of Organo-Bromine Compounds in Sediments of Lake Michigan.

Environ. Sci. Technol. 50 , 321-30, (2016)

Previously unreported natural and synthetic organo-bromine compounds (NSOBCs) have been found to contribute more than 99% of total organic bromine (TOB) in environmental matrices. We recently develope...