1-(4-pyridyl)piperazine

Names

[ Name ]:
1-(4-pyridyl)piperazine

[Synonym ]:
Piperazine, 1-(4-pyridinyl)-
1-(pyridin-4-yl)piperazine
1-pyridin-4-ylpiperazine
EINECS 213-764-7
MFCD00040745
1-(4-Pyridyl)Piperazine
1-(4-Pyridinyl)piperazine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
314.4±22.0 °C at 760 mmHg

[ Melting Point ]:
137-141 °C

[ Molecular Formula ]:
C₉H₁₃N₃

[ Molecular Weight ]:
163.220

[ Flash Point ]:
143.9±22.3 °C

[ Exact Mass ]:
163.110947

[ PSA ]:
28.16000

[ LogP ]:
0.12

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.547

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3259 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Benzyl-4-(4-pyridinyl) piperazine
Piperazine
4-chloropyridine
4-Bromopyridine
(R)-2-(2-chloro-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-4-ylamino)-3-methyl-butan-1-ol
[1-(2-chloro-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-4-ylamino)-cyclopropyl]-methanol
(2-chloro-5-oxo-6,7-dihydro-5H-5λ4-thieno[3,2-d]pyrimidin-4-yl)-(tetrahydropyran-4-yl)-amine
N-Boc-piperazine
2,4-Dichloro-6,7-dihydrothieno[3,2-d]pyrimidine
(R)-2-(2-chloro-6,7-dihydro-thieno[3,2-d]pyrimidin-4-ylamino)-3-methyl-butan-1-ol

DownStream

3,5-Dibromo-N-{6-(carboxyamino)-1-oxo-1-[4-(4-pyridinyl)-1-pipera zinyl]-2-hexanyl}tyrosinamide
1-(2,6-dichloropyridin-4-yl)piperazine

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

1-[(4-Pyridyl)Methyl]piperazine Hydrochloride
1,4-bis-(3-nitro-2-pyridyl)piperazine
1-(4-methoxy-3,5-dimethylbenzyl)-4-(3-(ethylamino)-2-pyridyl)piperazine hydrochloride
1-(4-Chloro-2-pyridinyl)piperazine
1-(4-Methyl-pyridin-2-yl)piperazine
1-(4-Trifluoromethyl-pyridin-2-yl)-piperazine
2-(4-chlorophenoxy)-N-((6-(furan-3-yl)pyridin-3-yl)methyl)acetamide
N-((6-(furan-3-yl)pyridin-3-yl)methyl)-2-(trifluoromethyl)benzamide
N-{[6-(furan-3-yl)pyridin-3-yl]methyl}-1-methanesulfonylpiperidine-4-carboxamide
2-bromo-N-((6-(furan-3-yl)pyridin-3-yl)methyl)-5-methoxybenzamide
1-(3,4-dimethylphenyl)-N-{[6-(furan-3-yl)pyridin-3-yl]methyl}-5-oxopyrrolidine-3-carboxamide
3-(4-fluoro-3-methylphenyl)-N-((6-(furan-3-yl)pyridin-3-yl)methyl)propanamide
2-(4-(4-fluorophenyl)-1H-pyrazol-1-yl)-N-((6-(furan-3-yl)pyridin-3-yl)methyl)acetamide
N-((6-(furan-3-yl)pyridin-3-yl)methyl)-4-(thiophen-2-yl)benzamide
N-((6-(furan-3-yl)pyridin-3-yl)methyl)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide
N-((6-(furan-3-yl)pyridin-3-yl)methyl)-1H-benzo[d]imidazole-5-carboxamide

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