holocalin(p)

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Names

[ CAS No. ]:
101-93-9

[ Name ]:
holocalin(p)

[Synonym ]:
Fenacaine
Holocaine
Phenacaine
Tanicaine

Chemical & Physical Properties

[ Density]:
1.04g/cm3

[ Boiling Point ]:
464.5ºC at 760mmHg

[ Melting Point ]:
117°C

[ Molecular Formula ]:
C18H22N2O2

[ Molecular Weight ]:
298.37900

[ Flash Point ]:
234.7ºC

[ Exact Mass ]:
298.16800

[ PSA ]:
42.85000

[ LogP ]:
4.71900

[ Vapour Pressure ]:
8.29E-09mmHg at 25°C

[ Index of Refraction ]:
1.534

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AD0350000
CHEMICAL NAME :
Acetamidine, N,N'-bis(p-ethoxyphenyl)-
CAS REGISTRY NUMBER :
101-93-9
BEILSTEIN REFERENCE NO. :
2702842
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C18-H22-N2-O2
MOLECULAR WEIGHT :
298.42
WISWESSER LINE NOTATION :
2OR DNUY1&MR DO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
53 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 12,190,1932

Safety Information

[ HS Code ]:
2925290090

Synthetic Route

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%


Related Compounds

  • holocalin
  • ethyl P-((diethylamino)(ethoxy)phosphino)-N,N-diethylphosphonamidate
  • 2-(p-Hydroxy-N-methylanilino)-1,4-benzochinon
  • 4-(p-tolylazo)aniline
  • α-(p-diethylaminophenyl)iminophenylacetonitrile
  • 5-(p-Toluenesulfonate)-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone
  • Methyl 2-((tert-butoxycarbonyl)amino)-5-methoxythiazole-4-carboxylate
  • 2-Chloro-6-fluoro-3,4-dimethoxybenzoic acid
  • 2-(1-((Tert-butyldiphenylsilyl)oxy)ethyl)thiazole
  • 2-Chloro-6-fluoro-3,4-dihydroxybenzoic acid
  • (15R)-15-hydroxy-16,16-dimethyl-1-oxa-6-thia-9,13-diazacycloheptadecane-2,5,10,14-tetrone
  • 1-[3-(Propan-2-yl)phenyl]ethane-1,2-diol
  • N-{[1,2,4]triazolo[1,5-a]pyridin-2-yl}prop-2-enamide
  • 7,8-difluoro-3-{4-[(4-fluorophenyl)methyl]-6,6-dimethyl-5,6-dihydro-4H-1,3-oxazin-2-yl}quinoline
  • N-cyclobutyl-N-(piperidin-4-yl)acetamide
  • 3-Amino-2,4-dibromobenzoic acid
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