4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido) phenoxy)picolinic acid

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Names

[ CAS No. ]:
1012058-78-4

[ Name ]:
4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido) phenoxy)picolinic acid

[Synonym ]:
4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinic acid
Sorafenib related compound 10

Chemical & Physical Properties

[ Molecular Formula ]:
C20H13ClF3N3O4

[ Molecular Weight ]:
451.78300

[ Exact Mass ]:
451.05500

[ PSA ]:
100.55000

[ LogP ]:
6.03430

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

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DownStream

  • Donafenib (Sorafenib D3)
  • METHYL 4-(4-(3-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREIDO)PHENOXY)PICOLINATE

Related Compounds

  • 6-Cyclopropyl-2-{4-[(5-fluoropyrimidin-4-yl)amino]cyclohexyl}-2,3-dihydropyridazin-3-one
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-{[Cyano(4-fluorophenyl)amino]methyl}cyclopropane-1-carbonitrile
  • tert-butyl N-{3',4'-dihydro-2'H-spiro[cyclobutane-1,1'-pyrrolo[1,2-a]pyrazine]-3-yl}carbamate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 3-Methylbutyl 5-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)oxy]-2-pyrazinecarboxylate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-(4-Fluorophenyl)-7,7-dimethyl-1H,4H,5H,6H,7H,8H-pyrazolo[4,3-c]azepine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol