Berberinol

Names

[ CAS No. ]:
10134-52-8

[ Name ]:
Berberinol

[Synonym ]:
9,10-dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-8-ol
8-BERBINOL,13,13a-DIDEHYDRO-9,10-DIMETHOXY-2,3-(METHYLENEDIOXY)
8-hydroxy-7,8-dihydroberberime
8-hydroxy-7,8-dihydroberberine
9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydro-8-berbinol
8-hydroxydihydroberberine
7,8-dihydro-8-hydroxyberberine

Chemical & Physical Properties

[ Density]:
1.44g/cm3

[ Boiling Point ]:
594.4ºC at 760mmHg

[ Molecular Formula ]:
C20H19NO5

[ Molecular Weight ]:
353.36900

[ Flash Point ]:
313.3ºC

[ Exact Mass ]:
353.12600

[ PSA ]:
60.39000

[ LogP ]:
2.73110

[ Vapour Pressure ]:
5.67E-15mmHg at 25°C

[ Index of Refraction ]:
1.7

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Berberine hydrochloride
  • Chloroform
  • Dihydroberberine
  • mercuric acetate
  • acetic acid
  • Tetrahydroberberine
  • Water

DownStream

  • Dihydroberberine
  • 8-Oxyberberine
  • methyl iodide
  • 1,3-Isobenzofurandione,4,5-dimethoxy-
  • 1,2-Benzenedicarboxylicacid, 3,4-dimethoxy-
  • 1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one,7,8-dihydro-
  • 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8-dihydro-9,10-dimethoxy-8-(trichloromethyl)-