Phosphoramide mustard

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Names

[ CAS No. ]:
10159-53-2

[ Name ]:
Phosphoramide mustard

[Synonym ]:
Phosphamide mustard
Friedman acid
Phosphorodiamidic mustard
Phosphoramide mustard
amino-[bis(2-chloroethyl)amino]phosphinic acid
Phosphorsaeure-amid-[bis-(2-chlor-aethyl)-amid]
N,N-Bis(2-chloroethyl)phosphorodiamidic acid
N,N-Bis-(2-chlor-aethyl)-diamidophosphorsaeure
N,N-bis-(2-chloro-ethyl)-diamidophosphoric acid
NLPD
ASTA 5317
N-Lost-phosphorsaeurediamid [German]

Chemical & Physical Properties

[ Density]:
1.474g/cm3

[ Boiling Point ]:
363.5ºC at 760mmHg

[ Molecular Formula ]:
C4H11Cl2N2O2P

[ Molecular Weight ]:
221.02200

[ Flash Point ]:
173.6ºC

[ Exact Mass ]:
219.99400

[ PSA ]:
76.37000

[ LogP ]:
1.52540

[ Vapour Pressure ]:
2.84E-06mmHg at 25°C

[ Index of Refraction ]:
1.525

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(amino-phenylmethoxy-phosphoryl)-2-chloro-N-(2-chloroethyl)ethanamine
  • N-(amino-phenoxy-phosphoryl)-2-chloro-N-(2-chloroethyl)ethanamine
  • 2-(4,4,6-trimethyltetrahydro-1,3-oxazin-2-yl)ethyl N,N-bis(2-chloroethyl)phosphorodiamidate
  • 2-(4,4,6-trimethyltetrahydro-1,3-oxazin-2-yl)ethyl N,N-bis(2-chloroethyl)-N'N'-morpholinophosphorodiamidate
  • 3-[amino-[bis(2-chloroethyl)amino]phosphoryl]oxy-1-phenyl-propan-1-one
  • acetaldophosphamide
  • aldophosphamide
  • 4-Hydroperoxy cyclophosphamide
  • 3-buten-1-(2-nitrophenyl) 1-N,N-bis(2-chloroethyl)phosphordiamidate

DownStream

  • Alcophosphamide

Related Compounds

  • isophosphoramide mustard
  • trophophosphoramide mustard
  • methyl phosphoramide mustard
  • carboxyethylphosphoramide mustard
  • Phosphoramide mustard (cyclohexanamine)
  • Phosphoramide mustard cyclohexamine salt
  • (R)-6-((3-Chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole
  • 4-(3-Bromophenyl)-6-(2-fluorophenyl)pyrimidin-2-amine
  • 4'-Methyl-epigallocatechin-3'-sulfate
  • 3-Tert-butyl-4-cyclopropoxypyridin-2-amine
  • Furaprofen, (S)-
  • 3-(3-(4'-Bromo(1,1'-biphenyl)-4-yl)-3-hydroxy-1-phenylpropyl)-4-hydroxy-2H-1-benzopyran-2-one
  • cyclo[Ac5c-DL-Trp-DL-Gln-DL-Pro-DL-Oic(3axi,7axi)-DL-Trp]
  • 2-(Aminomethyl)-6-(methylthio)phenol
  • Fenleuton, (S)-
  • cyclo[Ac5c-DL-Trp-DL-Lys(Bz)(Bz)-DL-Pro-DL-Oic(3axi,7axi)-DL-Trp]
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