Phosphoramide mustard

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Names

[ CAS No. ]:
10159-53-2

[ Name ]:
Phosphoramide mustard

[Synonym ]:
Phosphamide mustard
Friedman acid
Phosphorodiamidic mustard
Phosphoramide mustard
amino-[bis(2-chloroethyl)amino]phosphinic acid
Phosphorsaeure-amid-[bis-(2-chlor-aethyl)-amid]
N,N-Bis(2-chloroethyl)phosphorodiamidic acid
N,N-Bis-(2-chlor-aethyl)-diamidophosphorsaeure
N,N-bis-(2-chloro-ethyl)-diamidophosphoric acid
NLPD
ASTA 5317
N-Lost-phosphorsaeurediamid [German]

Chemical & Physical Properties

[ Density]:
1.474g/cm3

[ Boiling Point ]:
363.5ºC at 760mmHg

[ Molecular Formula ]:
C4H11Cl2N2O2P

[ Molecular Weight ]:
221.02200

[ Flash Point ]:
173.6ºC

[ Exact Mass ]:
219.99400

[ PSA ]:
76.37000

[ LogP ]:
1.52540

[ Vapour Pressure ]:
2.84E-06mmHg at 25°C

[ Index of Refraction ]:
1.525

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-(amino-phenylmethoxy-phosphoryl)-2-chloro-N-(2-chloroethyl)ethanamine
  • N-(amino-phenoxy-phosphoryl)-2-chloro-N-(2-chloroethyl)ethanamine
  • 2-(4,4,6-trimethyltetrahydro-1,3-oxazin-2-yl)ethyl N,N-bis(2-chloroethyl)phosphorodiamidate
  • 2-(4,4,6-trimethyltetrahydro-1,3-oxazin-2-yl)ethyl N,N-bis(2-chloroethyl)-N'N'-morpholinophosphorodiamidate
  • 3-[amino-[bis(2-chloroethyl)amino]phosphoryl]oxy-1-phenyl-propan-1-one
  • acetaldophosphamide
  • aldophosphamide
  • 4-Hydroperoxy cyclophosphamide
  • 3-buten-1-(2-nitrophenyl) 1-N,N-bis(2-chloroethyl)phosphordiamidate

DownStream

  • Alcophosphamide

Related Compounds

  • isophosphoramide mustard
  • trophophosphoramide mustard
  • methyl phosphoramide mustard
  • carboxyethylphosphoramide mustard
  • Phosphoramide mustard (cyclohexanamine)
  • Phosphoramide mustard cyclohexamine salt
  • (2S)-2-(tert-butoxy)-3-{[(prop-2-en-1-yloxy)carbonyl]amino}propanoic acid
  • (2S)-2-amino-3-(7-methoxynaphthalen-1-yl)propanoic acid
  • (2E)-3-[2-(1-acetylazetidin-3-yl)phenyl]prop-2-enoic acid
  • 3-Cyano-1-[(prop-2-en-1-yloxy)carbonyl]azetidine-3-carboxylic acid
  • 2-(1-Acetylazetidin-3-yl)-1,3-oxazole-4-carboxylic acid
  • 6-Acetamido-5-(hydroxymethyl)pyridine-3-carboxylic acid
  • 4-Cyclopropyl-2-acetamido-1,3-oxazole-5-carboxylic acid
  • 2-(1-acetylazetidin-3-yl)-2H-1,2,3-triazole-4-carboxylic acid
  • 1-[3-(5-nitro-1H-pyrazol-1-yl)azetidin-1-yl]ethan-1-one
  • 4-acetyl-4H,5H,6H,7H-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid
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