2-diethylamino-N,N-diphenyl-acetamide

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Names

[ CAS No. ]:
101784-86-5

[ Name ]:
2-diethylamino-N,N-diphenyl-acetamide

[Synonym ]:
LS-8941
N,N-diethyl-glycine diphenylamide
N,N-Diaethyl-glycin-diphenylamid

Chemical & Physical Properties

[ Density]:
1.082g/cm3

[ Boiling Point ]:
457.1ºC at 760 mmHg

[ Molecular Formula ]:
C18H22N2O

[ Molecular Weight ]:
282.38000

[ Flash Point ]:
198.2ºC

[ Exact Mass ]:
282.17300

[ PSA ]:
23.55000

[ LogP ]:
3.69310

[ Vapour Pressure ]:
1.54E-08mmHg at 25°C

[ Index of Refraction ]:
1.583

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB7058000
CHEMICAL NAME :
Acetamide, 2-(diethylamino)-N,N-diphenyl-
CAS REGISTRY NUMBER :
101784-86-5
BEILSTEIN REFERENCE NO. :
3345353
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C18-H22-N2-O
MOLECULAR WEIGHT :
282.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
132 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 23,331,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,402,1959

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 2-bromo-N,N-diphenyl-acetamide
  • 2-(diethylamino)-N,N-diethylacetamide
  • 2-(3,3-diphenyl-propylamino)-N,N-diphenyl-acetamide hydrochloride
  • S-[2-(diethylamino)ethyl] diphenyldithiocarbamate monohydrochloride
  • 2-(diethylamino)-N-methyl-N-(4-phenylsulfanylphenyl)acetamide,oxalic acid
  • 2-(diethylamino)-N-(3-phenylmethoxyphenyl)acetamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-2-(trifluoromethyl)-5-(trimethylsilyl)thiophene-3-carbaldehyde
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide