N-[3-[(2-hydroxyphenyl)methylamino]propyl]-2,2,5,5-tetramethyl-1H-pyrrole-3-carboxamide

Names

[ CAS No. ]:
102131-61-3

[ Name ]:
N-[3-[(2-hydroxyphenyl)methylamino]propyl]-2,2,5,5-tetramethyl-1H-pyrrole-3-carboxamide

[Synonym ]:
1H-Pyrrole-3-carboxamide,2,5-dihydro-N-(3-(((2-hydroxyphenyl)methyl)amino)propyl)-2,2,5,5-tetramethyl

Chemical & Physical Properties

[ Molecular Formula ]:
C19H29N3O2

[ Molecular Weight ]:
331.45200

[ Exact Mass ]:
331.22600

[ PSA ]:
76.88000

[ LogP ]:
3.63490

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UX9365100
CHEMICAL NAME :
1H-Pyrrole-3-carboxamide, 2,5-dihydro-N-(3-(((2-hydroxyphenyl)methyl)amino)prop yl)-2,2,5,5- tetramethyl-
CAS REGISTRY NUMBER :
102131-61-3
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H29-N3-O2
MOLECULAR WEIGHT :
331.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
28 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,1138,1986

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,5-dibromo-2,2,6,6-tetramethylpiperidin-4-one,hydrobromide
  • Salicylaldehyde

DownStream

Related Compounds

  • (2S,3R,4R,5S,6R)-2-(4-bromo-3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • (2S,3R,4R,5S,6R)-2-[4-cyclopropyl-3-(2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-phenyl]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
  • 2-(Thiazol-5-yl)morpholine
  • (2R,3S,4R,5R,6S)-2-Hydroxymethyl-6-[4-isopropyl-3-(1,2,3,4-tetrahydro-quinolin-7-ylmethyl)-phenyl]-tetrahydro-pyran-3,4,5-triol
  • N-[1-(1H-indol-3-ylcarbonyl)piperidin-4-yl]benzamide
  • N-benzyl-N-(cyanomethyl)-2-(2,6-dichlorophenyl)acetamide
  • N'-amino-3,5-dimethylbenzene-1-carboximidamide hydrochloride
  • 2-(2-Methylphenoxy)-1-(piperazin-1-yl)propan-1-one hydrochloride
  • ArisanschininA
  • 6-Bromo-2-(5-bromothiophen-2-yl)imidazo[1,2-a]pyridine