Boc-4-oxo-Pro-OMe

Suppliers

Names

[ Name ]:
Boc-4-oxo-Pro-OMe

[Synonym ]:
1-O-tert-butyl 2-O-methyl (2S)-4-oxopyrrolidine-1,2-dicarboxylate
Boc-4-Oxo-Pro-Ome
MFCD01861778
N-Boc-4-oxo-L-proline methyl ester

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
333.1±42.0 °C at 760 mmHg

[ Melting Point ]:
35-40ºC

[ Molecular Formula ]:
C₁₁H₁₇NO₅

[ Molecular Weight ]:
243.256

[ Flash Point ]:
155.3±27.9 °C

[ Exact Mass ]:
243.110672

[ PSA ]:
72.91000

[ LogP ]:
0.03

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.488

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302 + H312-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22;R41

[ Safety Phrases ]:
S26-S36/37-S39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Boc-Hyp-OMe
Oxalyl chloride
(2S)-methyl 1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylate
Dimethyl sulfoxide
Boc-Hyp-OH
N-methylmorpholine-N-oxide
Di-tert-butyl dicarbonate
(2S,4R)-METHYL 4-HYDROXYPYRROLIDINE-2-CARBOXYLATE
L-Hydroxyproline
H-Hyp-OMe hydrochloride

DownStream

(2S,4R)-Boc-4-Phenyl-pyrrolidine-2-carboxylic acid
(S)-tert-Butyl 4,4-difluoro-2-(hydroxymethyl)-pyrrolidine-1-carboxylate
Kainic acid
methyl n-boc-l-proline-3-ene
(S)-5-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid
N-t-BOC-4,4-Difluoro-L-proline methyl ester
N-t-BOC-4,4-Difluoro-L-Proline
(S)-5-tert-butyl 6-methyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate
L-Proline, 4-(difluoromethylene)-, methyl ester (9CI)

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%