2,2-Dibromo-2-cyanoacetamide

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Names

[ CAS No. ]:
10222-01-2

[ Name ]:
2,2-Dibromo-2-cyanoacetamide

[Synonym ]:
2,2-Dibromo-3-nitrilopropionamide
Cyanodibromoacetamide
EINECS 233-539-7
MFCD00129791
Dbnpa
ZVXEECN
Acetamide, 2,2-dibromo-2-cyano-
Dibromocyano acetic acid amide
dibromocyanoacetamide
2,2-Dibromo-2-cyanoacetamide
2-Cyano-2,2-dibromoacetamide
3-02-00-01641 (Beilstein Handbook Reference)
2,2-Dibromo-2-carbamoylacetonitrile

Chemical & Physical Properties

[ Density]:
2.5±0.1 g/cm3

[ Boiling Point ]:
221.5±40.0 °C at 760 mmHg

[ Melting Point ]:
122-125 °C(lit.)

[ Molecular Formula ]:
C3H2Br2N2O

[ Molecular Weight ]:
241.869

[ Flash Point ]:
87.8±27.3 °C

[ Exact Mass ]:
239.853378

[ PSA ]:
66.88000

[ LogP ]:
1.51

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.625

[ Storage condition ]:
Refrigerator

[ Stability ]:
Stable, but may be moisture sensitive. Incompatible with strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5956000
CHEMICAL NAME :
Acetamide, 2-cyano-2,2-dibromo-
CAS REGISTRY NUMBER :
10222-01-2
BEILSTEIN REFERENCE NO. :
1761192
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C3-H2-Br2-N2-O
MOLECULAR WEIGHT :
241.89
WISWESSER LINE NOTATION :
ZVXEECN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
PHMCAA Pharmacologist. (American Soc. for Pharmacology and Experimental Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1959- Volume(issue)/page/year: 15,226,1973
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
PHMCAA Pharmacologist. (American Soc. for Pharmacology and Experimental Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1959- Volume(issue)/page/year: 15,226,1973 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07898
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
118 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHMCAA Pharmacologist. (American Soc. for Pharmacology and Experimental Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014) V.1- 1959- Volume(issue)/page/year: 15,226,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1009 No. of Facilities: 369 (estimated) No. of Industries: 25 No. of Occupations: 10 No. of Employees: 9829 (estimated) No. of Female Employees: 108 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H317-H400

[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S26-S36/37/39-S45-S36/37

[ RIDADR ]:
UN 1759 8/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
AB5956000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2926909090

Synthetic Route

Precursor & DownStream

Precursor

  • Dibromomalononitrile
  • Malononitrile
  • 2-Cyanoacetamide

DownStream

  • dibromoacetonitrile
  • 1,1,2,2-Ethenetetracarboxylicacid, 1,1,2,2-tetraethyl ester
  • tetraethyl 1,1,2,2-ethanetetracarboxylate
  • 2,2-Dibromomalonamide
  • 4-Bromo-N,N-dimethylaniline
  • 2,2,2-Tribromoacetamide

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 2,2-dibromo-N-carbamoyl-2-cyanoacetamide
  • 2,2-dibromo-2-fluoro-1-(3-nitro-4-methoxy-phenyl)ethanol
  • 2,2-dibromo-2-ethoxy-4,5-benzo-1,3,2-dioxaphospholane
  • 2,2-dibromo-2-fluoroacetaldehyde
  • 2,2-dibromo-2-fluoroacetic acid
  • (2,2-dibromo-2-chloroethoxy)benzene
  • N-benzyl-N-ethyl-3-(pyrazin-2-yl)-1,2,4-oxadiazole-5-carboxamide
  • N-(3,4-dimethoxyphenyl)-2-((3-(3,5-dimethyl-1H-pyrazol-1-yl)pyrazin-2-yl)thio)acetamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine