2-amino-4-methoxy-N-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrimidine-5-carboxamide

Names

[ Name ]:
2-amino-4-methoxy-N-[[(2R)-1-methylpyrrolidin-2-yl]methyl]pyrimidine-5-carboxamide

[Synonym ]:
5-Pyrimidinecarboxamide,2-amino-N-((1-methyl-2-pyrrolidinyl)methyl)-4-methoxy-,(R)-(+)
(R)-(+)-2-Amino-N-((1-methyl-2-pyrrolidinyl)methyl)-4-methoxy-5-pyrimidinecarboxamide

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₉N₅O₂

[ Molecular Weight ]:
265.31200

[ Exact Mass ]:
265.15400

[ PSA ]:
93.37000

[ LogP ]:
0.80140

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV7706000

CHEMICAL NAME :: 5-Pyrimidinecarboxamide, 2-amino-N-((1-methyl-2-pyrrolidinyl)methyl)-4-methoxy -, (R)-(+)-

CAS REGISTRY NUMBER :: 102282-23-5

LAST UPDATED :: 198609

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H21-N5-O2

MOLECULAR WEIGHT :: 279.39

WISWESSER LINE NOTATION :: T6N CNJ BZ DO1 EVM1- BT5NTJ A2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,437,1982

Related Compounds

3-(4-{[(6-cyclopropylpyrimidin-4-yl)oxy]methyl}piperidine-1-carbonyl)-1-methyl-1H-indole
N-((6-cyclopropylpyridin-3-yl)methyl)-2-(2-oxobenzo[d]oxazol-3(2H)-yl)acetamide
N-(1-(3-(tert-butyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)azetidin-3-yl)-6-(cyclopentyloxy)-N-methylnicotinamide
N-((4-hydroxy-4,5,6,7-tetrahydrobenzofuran-4-yl)methyl)-4-(1H-pyrazol-1-yl)benzenesulfonamide
3-methyl-5-((3-oxo-4-(thiazol-2-yl)piperazin-1-yl)sulfonyl)benzo[d]oxazol-2(3H)-one
N-((6-cyclopropylpyridin-3-yl)methyl)-2-(1,3-dioxoisoindolin-2-yl)acetamide
4-((4-(2-Methyloxazol-4-yl)phenyl)sulfonyl)-1-(pyridin-2-yl)piperazin-2-one
3-oxo-4-(thiazol-2-yl)-N-(thiophen-2-yl)piperazine-1-carboxamide
N-((4-hydroxy-4,5,6,7-tetrahydrobenzofuran-4-yl)methyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide
N-(1-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)azetidin-3-yl)-N-methyl-1H-indole-5-carboxamide

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