(s)-(-)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyl-1,3-oxazolidine

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Names

[ Name ]:
(s)-(-)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyl-1,3-oxazolidine

[Synonym ]:
(4S)-2,2-Dimethyl-1,3-oxazolidine-4-carboxaldehyde, N-BOC protected
(S)-4-Formyl-2,2-dimethyl-oxazolidine-3-carboxylic tert-butyl ester
Garner's aldehyde
MFCD00209557
tert-Butyl (4S)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
tert-Butyl-(4S)-4-formyl-2,2-dimethyl-1,3-oxazolidin-3-carboxylat
(4S)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylic acid tert-butyl ester
(-)-Garner's Aldehyde
2-Methyl-2-propanyl (4S)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
(−)-N-Boc-N,O-isopropylidene-L-serinal
(S)-(-)-3-Boc-4-formyl-2,2-dimethyl-1,3-oxazolidine
3-Oxazolidinecarboxylic acid, 4-formyl-2,2-dimethyl-, 1,1-dimethylethyl ester, (4S)-
(-)-N-Boc-N,O-isopropylidene-L-serinal
Garners aldehyde
tert-Butyl (S)-(-)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate
(4S)-2,2-Dimethyl-1,3-oxazolidine-4-carboxaldehyde N-BOC protected
(S)-(-)-3-(tert-Butoxycarbonyl)-4-forMyl-2,2-diMethyl-1,3-oxazolidine
(4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
302.7±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₉NO₄

[ Molecular Weight ]:
229.27

[ Flash Point ]:
136.9±27.9 °C

[ Exact Mass ]:
229.131409

[ PSA ]:
55.84000

[ LogP ]:
1.15

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.500

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(R)-N-Boc-2,2-Dimethyl-4-hydroxymethyloxazolindine
(R)-3-tert-butyl 4-methyl 2,2-dimethyloxazolidine-3,4-dicarboxylate
(S)-3-BOC-4-(METHOXYMETHYLCARBAMOYL)-2,2-DIMETHYLOXAZOLIDINE
Boc-Ser-OMe
Boc-Ser-OH
Di-tert-butyl dicarbonate
BOC-ON

DownStream

tert-butyl (4S)-4-[(S)-hydroxy-[(2S)-5-oxo-2H-furan-2-yl]methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
tert-butyl (4S)-4-[(R)-hydroxy-[(2R)-5-oxo-2H-furan-2-yl]methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
(R)-N-Boc-2,2-Dimethyl-4-hydroxymethyloxazolindine
tert-butyl (4S)-4-[(1R,2E)-1-hydroxy-2-hexadecenyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
tert-butyl (4S)-4-[(1S,2E)-1-hydroxy-2-hexadecenyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate
trans-[4S,4(1'S)]-4-(1'-hydroxy-3'-phenyl-2'-propenyl)-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester
Carbamic acid, (1-methylene-2-propynyl)-, 1,1-dimethylethyl ester (9CI)
1,2,3,4-Tetra-O-acetyl-5-(2,2-dimethyl-3-{[(2-methyl-2-propanyl)o xy]carbonyl}-1,3-oxazolidin-4-yl)pentopyranose
2-Methyl-2-propanyl 2,2-dimethyl-4-({5-oxo-3,4-bis[(trimethylsily l)oxy]tetrahydro-2-furanyl}[(trimethylsilyl)oxy]methyl)-1,3-oxazo lidine-3-carboxylate (non-preferred name)

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Hoemann, M.Z. et al.

Tetrahedron Lett. 37 , 953, (1996)

Roush, W.R. Hunt, J.A.

J. Org. Chem. 60 , 798, (1995)

Guibourdenche, C. et al.

Tetrahedron Asymmetry 4 , 2041, (1993)

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