2-[1H-indol-3-yl(phenyl)methyl]-1-azabicyclo[2.2.2]octan-3-one,hydrochloride

Names

[ CAS No. ]:
102338-84-1

[ Name ]:
2-[1H-indol-3-yl(phenyl)methyl]-1-azabicyclo[2.2.2]octan-3-one,hydrochloride

[Synonym ]:
4-<(3'-Indolyl)benzyl>-3-hydroxyquinuclidine hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C22H23ClN2O

[ Molecular Weight ]:
366.88400

[ Exact Mass ]:
366.15000

[ PSA ]:
36.10000

[ LogP ]:
4.70300

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VD7186000
CHEMICAL NAME :
3-Quinuclidinone, 2-(alpha-(3-indolyl)benzyl)-, monohydrochloride
CAS REGISTRY NUMBER :
102338-84-1
LAST UPDATED :
198609
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H22-N2-O.Cl-H
MOLECULAR WEIGHT :
366.92
WISWESSER LINE NOTATION :
T66 A B AV CNTJ BYR&- DT56 BMJ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
46 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - muscle contraction or spasticity Skin and Appendages - hair
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,345,1981

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • C15H24ClN5O3S
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-[4-[[5-(Trifluoromethyl)-2-pyridinyl]oxy]phenoxy]butanoic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine