1-butyl-3-[(4-chlorophenyl)-phenyl-methoxy]pyrrolidine

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Names

[ CAS No. ]:
102446-17-3

[ Name ]:
1-butyl-3-[(4-chlorophenyl)-phenyl-methoxy]pyrrolidine

[Synonym ]:
ahr 225

Chemical & Physical Properties

[ Density]:
1.13g/cm3

[ Boiling Point ]:
433.5ºC at 760mmHg

[ Molecular Formula ]:
C21H26ClNO

[ Molecular Weight ]:
343.89000

[ Flash Point ]:
216ºC

[ Exact Mass ]:
343.17000

[ PSA ]:
12.47000

[ LogP ]:
5.25830

[ Vapour Pressure ]:
1.02E-07mmHg at 25°C

[ Index of Refraction ]:
1.583

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY0705100
CHEMICAL NAME :
Pyrrolidine, 3-(p-chloro-alpha-phenylbenzyloxy)-1-butyl-
CAS REGISTRY NUMBER :
102446-17-3
BEILSTEIN REFERENCE NO. :
0281898
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H26-Cl-N-O
MOLECULAR WEIGHT :
343.93
WISWESSER LINE NOTATION :
T5NTJ A4 COYR&R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,73,1959

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-(4-Bromophenyl)-3-(5-chloro-2-hydroxy-4-methylphenyl)-5-(2-hydroxyethyl)-1,2,3,3a,4,6a-hexahydropyrrolo[3,4-c]pyrazol-6-one
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • (3R)-3-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pentanamido}hexanoic acid
  • 2-Chloro-4-(1-ethoxyethenyl)thieno[2,3-d]pyrimidine
  • benzyl N-[7-(fluorosulfonyl)-1,5-dimethyl-1H-indazol-3-yl]carbamate