3-(1-methylpyrrolidin-2-yl)propyl 2-hydroxy-2,2-diphenylacetate

Names

[ CAS No. ]:
102476-69-7

[ Name ]:
3-(1-methylpyrrolidin-2-yl)propyl 2-hydroxy-2,2-diphenylacetate

[Synonym ]:
Benzilsaeure-[3-(1-methyl-pyrrolidin-2-yl)-propylester]
2-Pyrrolidinepropanol,1-methyl-,benzilate
Benzilsaeure-<3-(1-methyl-pyrrolidyl-(2))-propylester>
BENZILIC ACID,3-(1-METHYL-2-PYRROLIDINYL)PROPYL ESTER
BRL 490
benzilic acid-[3-(1-methyl-pyrrolidin-2-yl)-propyl ester]

Chemical & Physical Properties

[ Density]:
1.131g/cm3

[ Boiling Point ]:
441.9ºC at 760mmHg

[ Molecular Formula ]:
C22H27NO3

[ Molecular Weight ]:
353.45500

[ Flash Point ]:
221.1ºC

[ Exact Mass ]:
353.19900

[ PSA ]:
49.77000

[ LogP ]:
3.27800

[ Vapour Pressure ]:
1.37E-08mmHg at 25°C

[ Index of Refraction ]:
1.564

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DD4029500
CHEMICAL NAME :
Benzilic acid, 3-(1-methyl-2-pyrrolidinyl)propyl ester
CAS REGISTRY NUMBER :
102476-69-7
BEILSTEIN REFERENCE NO. :
0313593
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C22-H27-N-O3
MOLECULAR WEIGHT :
353.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
11500 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 12,447,1957

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-chloro-2,2-diphenylacetyl chloride

DownStream

Related Compounds

  • Tert-butyl 2-(prop-2-en-1-yl)pyrrolidine-2-carboxylate
  • 1-{[(Benzyloxy)carbonyl](methyl)amino}-3,3-difluorocyclobutane-1-carboxylic acid
  • N-[(4-methyl-1,3-thiazol-5-yl)methyl]-1,4-oxazepan-6-amine
  • [1-(2,2-Difluoroethyl)cyclobutyl]methanesulfonamide
  • 4-{[(Benzyloxy)carbonyl]amino}-2-oxabicyclo[2.2.1]heptane-1-carboxylic acid
  • 2-(3-{[(Benzyloxy)carbonyl]amino}bicyclo[1.1.1]pentan-1-yl)acetic acid
  • 5-Chloro-3-methyl-1-benzofuran-2-sulfonamide
  • (1R,2S,6R,7S)-4-azatricyclo[5.3.0.0,2,6]decane-9-carboxylic acid
  • ethyl (1R,2S,6R,7S)-4-azatricyclo[5.3.0.0,2,6]decane-9-carboxylate
  • (1R,2S,6R,7S)-4-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-azatricyclo[5.3.0.0,2,6]decane-9-carboxylic acid
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