methyl 2,4,6-trideoxy-3(R)-(tert-butyldimethylsiloxy)-(5R)-6-(2-propenyl)-α-D-allopyranose

Names

[ CAS No. ]:
102538-28-3

[ Name ]:
methyl 2,4,6-trideoxy-3(R)-(tert-butyldimethylsiloxy)-(5R)-6-(2-propenyl)-α-D-allopyranose

Chemical & Physical Properties

[ Molecular Formula ]:
C16H32O3Si

[ Molecular Weight ]:
300.50900

[ Exact Mass ]:
300.21200

[ PSA ]:
27.69000

[ LogP ]:
4.49450

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (4S,5S)-2β-methoxy-4-hydroxy-6-hydroxymethylenetetrahydropyran
  • methyl 2,4-dideoxy-(5R)-6-(phenoxythioxomethyl)-α-D-allopyranose

DownStream

  • Mevastatin
  • methyl 2,4,6-trideoxy-3(R)-(tert-butyldimethylsiloxy)-(5R)-6-(4-oxo-2,7,8,10-dodecatetraenyl)-α-D-allopyranoside
  • (S)-(1S,7S,8S,8aR)-8-(2-((2R,4R,6S)-4-((tert-butyldimethylsilyl)oxy)-6-methoxytetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate