3-[(3-chloro-4-ethoxy-phenyl)methyl]-5-fluoro-1H-pyrimidine-2,4-dione

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Names

[ CAS No. ]:
102613-21-8

[ Name ]:
3-[(3-chloro-4-ethoxy-phenyl)methyl]-5-fluoro-1H-pyrimidine-2,4-dione

[Synonym ]:
2,4(1H,3H)-Pyrimidinedione,3-[(3-chloro-4-ethoxyphenyl)methyl]-5-fluoro
3-(3-Chloro-4-ethoxybenzyl)-5-fluorouracil
Uracil,3-(3-chloro-4-ethoxybenzyl)-5-fluoro
3-[(3-CHLORO-4-ETHOXY-PHENYL)METHYL]-5-FLUORO-1H-PYRIMIDINE-2,4-DIONE

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Molecular Formula ]:
C13H12ClFN2O3

[ Molecular Weight ]:
298.69700

[ Exact Mass ]:
298.05200

[ PSA ]:
64.35000

[ LogP ]:
2.18840

[ Index of Refraction ]:
1.595

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ9421000
CHEMICAL NAME :
Uracil, 3-(3-chloro-4-ethoxybenzyl)-5-fluoro-
CAS REGISTRY NUMBER :
102613-21-8
LAST UPDATED :
198609
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H12-Cl-F-N2-O3
MOLECULAR WEIGHT :
298.72
WISWESSER LINE NOTATION :
T6NVMVJ A1R CG DO2& EF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
579 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 12,586,1978

Related Compounds

  • 1-(10-Azidodecanoyl)pyrrolidine-3-carboxylic acid
  • 1-(2-Formylphenyl)azetidine-2-carboxamide
  • (1-{5H,6H,7H-cyclopenta[b]pyrazin-2-yl}azetidin-2-yl)methanamine
  • {1-[(1,5-dimethyl-1H-pyrazol-3-yl)methyl]azetidin-2-yl}methanamine
  • {1-[(3-Methoxyoxolan-3-yl)methyl]azetidin-2-yl}methanamine
  • tert-butyl N-[4-amino-5-(4-chloro-3-methylphenyl)pentyl]carbamate
  • tert-butyl N-[3-amino-4-(4-chloro-3-methylphenyl)butan-2-yl]-N-methylcarbamate
  • 4-{[1-(Bromomethyl)cyclobutyl]methyl}-1-chloro-2-methylbenzene
  • 4-{[1-(Bromomethyl)-2-methylcyclopropyl]methyl}-1-chloro-2-methylbenzene
  • 1-Chloro-4-[3-chloro-2-(chloromethyl)-2-methylpropyl]-2-methylbenzene