VX-222

Suppliers

Names

[ CAS No. ]:
1026785-55-6

[ Name ]:
VX-222

[Synonym ]:
5-(3,3-Dimethyl-1-butyn-1-yl)-3-{(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino}-2-thiophenecarboxylic acid
VX222
VCH222
5-(3,3-dimethylbut-1-ynyl)-3-[(trans-4-hydroxycyclohexyl)-(4-trans-methylcyclohexanecarbonyl)amino]thiophene-2-carboxylic acid
5-(3,3-dimethylbut-1-ynyl)-3-((1r,4r)-N-(4-hydroxycyclohexyl)-4-methylcyclohexanecarboxamido)thiophene-2-carboxylic acid
2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-
5-(3,3-dimethylbut-1-ynyl)-3-{(trans-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino}thiophene-2-carboxylic acid
VX-222
VX-222 (VCH-222,Lomibuvir)
5-(3,3-dimethylbut-1-ynyl)-3-[(trans-4-hydroxycyclohexyl)-(trans-4-methylcyclohexanecarbonyl)amino]thiophene-2-carboxylic acid
Lomibuvir

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
640.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H35NO4S

[ Molecular Weight ]:
445.615

[ Flash Point ]:
341.2±31.5 °C

[ Exact Mass ]:
445.228668

[ PSA ]:
106.08000

[ LogP ]:
5.15

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.589

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 5-(3,3-dimethylbut-1-ynyl)-3-[(trans-4-hydroxycyclohexyl)-(trans-4-methylcyclohexanecarbonyl)amino]thiophene-2-carboxylate
  • cis-4-methylcyclohexanecarboxylic acid
  • trans-4-Methylcyclohexane-1-carbonyl chloride
  • Methyl 3-amino-2-thiophenecarboxylate
  • 1,4-Dioxaspiro[4.5]decan-8-one

DownStream

Related Compounds

  • vx-222
  • VX-770
  • VX-984
  • vx
  • VX-745
  • VX-765
  • (6-(1H-pyrazol-1-yl)pyridazin-3-yl)(4-(methylsulfonyl)piperazin-1-yl)methanone
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide