N-heptyl-4-methoxy-7,7-dimethyl-8,10-dihydropyrimido[5,4-b][1,4]benzothiazin-9-amine

Names

[ CAS No. ]:
102688-88-0

[ Name ]:
N-heptyl-4-methoxy-7,7-dimethyl-8,10-dihydropyrimido[5,4-b][1,4]benzothiazin-9-amine

[Synonym ]:
6H-Pyrimido[4,5-b][1,4]benzothiazin-9-amine,N-heptyl-7,8-dihydro-4-methoxy-7,7-dimethyl

Chemical & Physical Properties

[ Molecular Formula ]:
C20H30N4OS

[ Molecular Weight ]:
374.54300

[ Exact Mass ]:
374.21400

[ PSA ]:
84.37000

[ LogP ]:
5.61710

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UW7681520
CHEMICAL NAME :
6H-Pyrimido(4,5-b)(1,4)benzothiazin-9-amine, 7,8-dihydro-7,7-dimethyl-N-heptyl-4-methoxy-
CAS REGISTRY NUMBER :
102688-88-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H30-N4-O-S
MOLECULAR WEIGHT :
374.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
370 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 19,459,1985

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-[2-({[4-(3,4-dimethoxyphenyl)-2,6-dioxocyclohexylidene]methyl}amino)ethyl]-N-(prop-2-en-1-yl)piperazine-1-carbothioamide
  • (3S,4R)-4-(2,4-Difluorophenyl)-1-(oxan-4-yl)pyrrolidine-3-carboxylic acid;hydrochloride
  • 2-(((2-Fluoro-5-(trifluoromethyl)phenyl)amino)ethylidene)indane-1,3-dione
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • N-{[4-(furan-2-yl)thiophen-2-yl]methyl}-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine