Levetiracetam

Suppliers

Names

[ Name ]:
Levetiracetam

[Synonym ]:
(2S)-2-(2-Oxopyrrolidin-1-yl)butanamide
levetiracetamum
2(S)-(2-oxopyrrolidin-1-yl)butyramide
KEPPRA
(2S)-2-(2-Oxo-1-pyrrolidinyl)butanamide
(S)-Etiracetam
Etiracetam levo-isomer
EINECS 200-659-6
ucb L059
(aS)-a-Ethyl-2-oxo-1-pyrrolidineacetamide
1-pyrrolidineacetamide, a-ethyl-2-oxo-, (aS)-
1-Pyrrolidineacetamide, α-ethyl-2-oxo-, (αS)-
(S)-2-(2-Oxopyrrolidin-1-yl)Butanamide
SIB S1
(S)-2-(2-Oxo-1-pyrrolidinyl)butyramide
MFCD03265610
SIB-S1
(-)-(S)-α-Ethyl-2-oxo-1-pyrrolidineacetamide
Keppra XR
Levetiracetam

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
395.9±25.0 °C at 760 mmHg

[ Melting Point ]:
118-119°C

[ Molecular Formula ]:
C₈H₁₄N₂O₂

[ Molecular Weight ]:
170.209

[ Flash Point ]:
193.2±23.2 °C

[ Exact Mass ]:
170.105530

[ PSA ]:
63.40000

[ LogP ]:
-0.67

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.519

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UX9656166

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2S)-2-(2-Oxo-1-pyrrolidinyl)butanoic acid
(S)-methyl 2-(2-oxopyrrolidin-1-yl)-2-butanoate
2,5-Dimethoxy-2,5-dihydrofuran
2-Aminobutanamide
2-Aminobutanamide
4-Chlorobutyryl chloride
Ethyl chloroformate
methyl-(S)-4-(1-carbamoylpropylamino)butyrate hydrochloride

DownStream

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Development of a SPE-HPLC-MS/MS method for the determination of most prescribed pharmaceuticals and related metabolites in urban sewage samples.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 990 , 23-30, (2015)

Based on regional prescription data several pharmaceuticals with variable amounts of prescription and corresponding metabolites were selected and analyzed in influent and effluent samples of the sewag...

Determining the polymer threshold amount for achieving robust drug release from HPMC and HPC matrix tablets containing a high-dose BCS class I model drug: in vitro and in vivo studies.

AAPS PharmSciTech 16(2) , 398-406, (2015)

It is challenging to achieve mechanically robust drug-release profiles from hydrophilic matrices containing a high dose of a drug with good solubility. However, a mechanically robust drug release over...

Determination of a selection of anti-epileptic drugs and two active metabolites in whole blood by reversed phase UPLC-MS/MS and some examples of application of the method in forensic toxicology cases.

Drug Test. Anal. 7 , 634-44, (2015)

Quantitative determination of anti-epileptic drug concentrations is of great importance in forensic toxicology cases. Although the drugs are not usually abused, they are important post-mortem cases wh...