(R)-5-Hydroxypiperidin-2-one

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Names

[ Name ]:
(R)-5-Hydroxypiperidin-2-one

[Synonym ]:
(5R)-5-Hydroxy-2-piperidinone
(5R)-5-hydroxypiperidin-2-one
(R)-5-Hydroxy-piperidin-2-one
2-Piperidinone, 5-hydroxy-, (5R)-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
352.3±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₉NO₂

[ Molecular Weight ]:
115.131

[ Flash Point ]:
166.8±25.9 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
49.33000

[ LogP ]:
-2.16

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.498

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(S)-(+)-5-Azidomethyl-2-oxotetrahydrofuran
(5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone
(S)-(+)-5-Mesyloxymethyl-2-oxotetrahydrofuran

DownStream

(4R)-5-amino-4-hydroxypentanoic acid
(3R)-3-Piperidinol

Related Compounds

(S)-5-HYDROXYPIPERIDIN-2-ONE
1-benzyl-5-hydroxypiperidin-2-one
(S)-1-benzyl-5-hydroxypiperidin-2-one
3,3-difluoro-5-hydroxypiperidin-2-one
(4S,5R)-4-(4-fluorophenyl)-5-hydroxypiperidin-2-one
5-HYDROXYPIPERIDIN-2-ONE
3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{[2-(propan-2-yl)cyclohexyl]carbamoyl}propanoic acid
3-[2-(Morpholin-4-yl)-1,3-thiazol-5-yl]propanenitrile
2-[2-(Dimethylamino)-3,4-difluorophenoxy]acetic acid
O-{[1-(1-phenyl-1H-pyrazol-4-yl)cyclopropyl]methyl}hydroxylamine
tert-butyl N-{2-chloro-5-[(3-hydroxyazetidin-3-yl)methyl]phenyl}carbamate
Tert-butyl 2-[3-(trifluoromethyl)pyridin-4-yl]piperazine-1-carboxylate
1-[(5-Bromo-2-chlorophenyl)methyl]cyclopropane-1-carboxylic acid
2-(1-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclobutaneamido}cyclopentyl)acetic acid
Methyl 4-amino-5-(methylsulfanyl)pent-2-ynoate
2-bromo-1-(5-chloro-1H-indol-2-yl)ethan-1-ol

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