(R)-5-Hydroxypiperidin-2-one

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Names

[ Name ]:
(R)-5-Hydroxypiperidin-2-one

[Synonym ]:
(5R)-5-Hydroxy-2-piperidinone
(5R)-5-hydroxypiperidin-2-one
(R)-5-Hydroxy-piperidin-2-one
2-Piperidinone, 5-hydroxy-, (5R)-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
352.3±35.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅H₉NO₂

[ Molecular Weight ]:
115.131

[ Flash Point ]:
166.8±25.9 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
49.33000

[ LogP ]:
-2.16

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.498

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(S)-(+)-5-Azidomethyl-2-oxotetrahydrofuran
(5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone
(S)-(+)-5-Mesyloxymethyl-2-oxotetrahydrofuran

DownStream

(4R)-5-amino-4-hydroxypentanoic acid
(3R)-3-Piperidinol

Related Compounds

(S)-5-HYDROXYPIPERIDIN-2-ONE
1-benzyl-5-hydroxypiperidin-2-one
(S)-1-benzyl-5-hydroxypiperidin-2-one
3,3-difluoro-5-hydroxypiperidin-2-one
(4S,5R)-4-(4-fluorophenyl)-5-hydroxypiperidin-2-one
5-HYDROXYPIPERIDIN-2-ONE
1-[1-(3-Bromo-4-hydroxy-5-methoxyphenyl)cyclopropyl]ethan-1-one
1-(2-Bromo-3-nitrophenyl)cyclopropane-1-carboxylic acid
2-Amino-1-(2-bromo-3-nitrophenyl)ethan-1-ol
(1S)-1-(2-bromo-3-nitrophenyl)ethan-1-ol
3-[(2-Bromo-3-nitrophenyl)methyl]pyrrolidine
O-[2-(2-bromo-3-nitrophenyl)propyl]hydroxylamine
(1R)-2-amino-1-(3-bromo-5-chloro-2-methoxyphenyl)ethan-1-ol
(2S)-2-amino-2-(3-bromo-5-chloro-2-methoxyphenyl)ethan-1-ol
1-(3-Bromo-5-chloro-2-methoxyphenyl)prop-2-en-1-ol
2-(3-Bromo-5-chloro-2-methoxyphenyl)azetidine

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