3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine,3-β-D-ribofuranosyl-

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Names

[ CAS No. ]:
10299-44-2

[ Name ]:
3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine,3-β-D-ribofuranosyl-

[Synonym ]:
8-aza-adenosine
8-Aza-adenosin

Chemical & Physical Properties

[ Density]:
2.29 g/cm3

[ Boiling Point ]:
702.6ºC at 760 mmHg

[ Molecular Formula ]:
C₉H₁₂N₆O₄

[ Molecular Weight ]:
268.22900

[ Flash Point ]:
378.7ºC

[ Exact Mass ]:
268.09200

[ PSA ]:
152.43000

[ Vapour Pressure ]:
1.01E-20mmHg at 25°C

[ Index of Refraction ]:
2

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ5718000

CHEMICAL NAME :: 3H-1,2,3-Triazolo(4,5-d)pyrimidin-7-amine, 3-beta-D-ribofuranosyl-

CAS REGISTRY NUMBER :: 10299-44-2

LAST UPDATED :: 199709

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H12-N6-O4

MOLECULAR WEIGHT :: 268.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 169 mg/kg/5D-I

TOXIC EFFECTS :: Endocrine - hypoglycemia Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 10 umol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 31,3207,1982

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36