CHLOROACETAMIDINE HYDROCHLORIDE

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Names

[ CAS No. ]:
10300-69-3

[ Name ]:
CHLOROACETAMIDINE HYDROCHLORIDE

[Synonym ]:
Ethanimidamide, 2-chloro-, hydrochloride (1:1)
2-chloroacetimidamide hydrochloride
EINECS 233-675-7
2-Chloracetamidine hydrochloride
2-chloroacetamidine monohydrochloride
2-chloroacetamidine
2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE
CHLOROACETAMIDINE HYDROCHLORIDE
MFCD00053013
BUTTPARK 44 3-88
CHLORACETAMIDINE HYDROCHLORIDE
2-Chlor-acetamidin,Hydrochlorid
2-Chloroethanimidamide hydrochloride (1:1)
2-CHLORORACETAMIDINE HYDROCHLORIDE
ChloroacetamidineHCl
EthaniMidaMide,2-chloro-,Monohydrochloride
Ethanimidamide, 2-chloro-, monohydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
146.4ºC at 760 mmHg

[ Melting Point ]:
98-103 °C(lit.)

[ Molecular Formula ]:
C2H6Cl2N2

[ Molecular Weight ]:
128.988

[ Flash Point ]:
42.4ºC

[ Exact Mass ]:
127.990807

[ PSA ]:
49.87000

[ LogP ]:
1.76320

[ Vapour Pressure ]:
4.64mmHg at 25°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
UN3261

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-chloroacetonitrile
  • O-methyl 2-chloroacetimidate

DownStream

  • 2-(Chloromethyl)-4-pyrimidinamine
  • 5-Chloro-3-(chloromethyl)-1,2,4-thiadiazole
  • 2-(Chloromethyl)pyrimidine
  • Thiosulfuric acid,S-(2-amino-2-iminoethyl) ester
  • 2-(Chloromethyl)-6-methyl-4(1H)-pyrimidinone
  • 5-(4-bromophenyl)-2-(chloromethyl)-4-(2,4-dichlorophenyl)pyrimidine
  • 2-sulfanylethanimidamide

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.

Dis. Model Mech. 6 , 467-78, (2013)

Multiple sclerosis (MS) is the most common CNS-demyelinating disease of humans, showing clinical and pathological heterogeneity and a general resistance to therapy. We first discovered that abnormal m...


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Related Compounds

  • N-Benzyl-2-chloroacetamidine Hydrochloride
  • N,N-dimethylchloroacetamidine hydrochloride
  • N-(1-hydroxy-4-adamantyl)-2-chloroacetamidine hydrochloride
  • 2-chloroacetamidine
  • carnitine hydrochloride
  • Triprolidine hydrochloride
  • 2-[N-(2,2-dimethylpropyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-enamido]acetic acid
  • 1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-pyrrol-2-yl)propanoyl]pyrrolidine-3-carboxylic acid
  • 4-({3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)but-2-enoic acid
  • 2-[2-({3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-3-yl}formamido)ethoxy]acetic acid
  • rac-3-[N-(cyclopropylmethyl)-1-[(1R,2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido]propanoic acid
  • 1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]-4-(trifluoromethyl)pyrrolidine-3-carboxylic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-({spiro[2.3]hexan-1-yl}carbamoyl)propanoic acid
  • (3S)-3-{[(tert-butoxy)carbonyl]amino}-3-[3-fluoro-5-(trifluoromethyl)phenyl]propanoic acid
  • 4-[3-(dimethylamino)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]butanoic acid
  • 2-(4-{3-[benzyl(methyl)amino]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido}phenyl)acetic acid
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