5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

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Names

[ CAS No. ]:
103003-96-9

[ Name ]:
5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

[Synonym ]:
N-(4-(1,3-Diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)-L-glutamic acid
5,10-Methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin
L-Glutamic acid,N-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)
Mthdaz

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Molecular Formula ]:
C22H26N6O5

[ Molecular Weight ]:
454.47900

[ Exact Mass ]:
454.19600

[ PSA ]:
186.22000

[ LogP ]:
1.31360

[ Index of Refraction ]:
1.704

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-diethyl 2-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido[5,4-e]indolizin-8-yl)benzamido)pentanedioate
  • H-Glu(OEt)-OEt.HCl
  • methyl 4-amino-4-deoxy-5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazapteroate

DownStream

Related Compounds

  • 6-[Ethyl(prop-2-yn-1-yl)amino]pyridazine-3-carboxylic acid
  • Methyl 4-amino-3-[(cyclobutylmethyl)amino]benzoate
  • 3-amino-2-(5-methyl-2-furyl)propanoic acid
  • 3-(2,5-dimethyloxazol-4-yl)propanoic acid
  • 3-(2,4-dimethyloxazol-5-yl)propanoic acid
  • 2,4-Dibromo-6-chloro-3-(trifluoromethyl)aniline
  • 2-(Trifluoromethyl)butane-1,2-diol
  • 4-(3-methylisoxazol-5-yl)butanoic acid
  • 1-(1-methyl-5-nitro-pyrazol-3-yl)ethanone
  • 6,8-dihydro-5H-[1,2,4]triazolo[3,4-c][1,4]oxazine-3-carboxylic acid
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