5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

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Names

[ CAS No. ]:
103003-96-9

[ Name ]:
5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

[Synonym ]:
N-(4-(1,3-Diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)-L-glutamic acid
5,10-Methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin
L-Glutamic acid,N-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)
Mthdaz

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Molecular Formula ]:
C22H26N6O5

[ Molecular Weight ]:
454.47900

[ Exact Mass ]:
454.19600

[ PSA ]:
186.22000

[ LogP ]:
1.31360

[ Index of Refraction ]:
1.704

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-diethyl 2-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido[5,4-e]indolizin-8-yl)benzamido)pentanedioate
  • H-Glu(OEt)-OEt.HCl
  • methyl 4-amino-4-deoxy-5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazapteroate

DownStream

Related Compounds

  • 1,1-Dimethyl-1,2-dihydroisoquinolin-3(4H)-one
  • (2-(2-Methylallyl)phenyl)boronic acid
  • 5-(1,3-Dioxolan-2-yl)thiophene-2-carbaldehyde
  • 5-Benzoyl-2-furancarboxaldehyde
  • 2-Bromo-4-(methylthio)benzo[d]oxazole
  • 5H,6H,7H,8H-pyrido[4,3-d]pyrimidine-2,4-diamine
  • Elzasonan metabolite M3
  • 5-Bromo-5-methylhexan-2-one
  • 5-bromo-8-nitro-2-methylisoquinolin-1(2H)-one
  • Levonorgestrel cyclopropylcarboxylate
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