5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

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Names

[ CAS No. ]:
103003-96-9

[ Name ]:
5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

[Synonym ]:
N-(4-(1,3-Diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)-L-glutamic acid
5,10-Methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin
L-Glutamic acid,N-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)
Mthdaz

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Molecular Formula ]:
C22H26N6O5

[ Molecular Weight ]:
454.47900

[ Exact Mass ]:
454.19600

[ PSA ]:
186.22000

[ LogP ]:
1.31360

[ Index of Refraction ]:
1.704

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-diethyl 2-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido[5,4-e]indolizin-8-yl)benzamido)pentanedioate
  • H-Glu(OEt)-OEt.HCl
  • methyl 4-amino-4-deoxy-5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazapteroate

DownStream

Related Compounds

  • 3-(3,5-Dimethylpiperidin-1-yl)-7-oxaspiro[3.5]nonan-1-amine
  • 3-(4-Ethyl-4-methylpiperidin-1-yl)-7-oxaspiro[3.5]nonan-1-amine
  • methyl (2Z)-3-(oxan-3-yl)pent-2-enoate
  • 3-(2-methylbutan-2-yl)-1-(octahydro-1H-indol-3a-yl)urea
  • 3a-amino-N-(2-methylpropyl)-octahydro-1H-indole-1-carboxamide
  • 6-(Ethoxycarbonyl)-2-oxo-1,2,5,6,7,8-hexahydro-1,6-naphthyridine-3-carboxylic acid
  • Methyl 4-(2-azido-1-hydroxyethyl)benzoate
  • 4-({1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}formamido)-3-methylbutanoic acid
  • 3-Hydroxy-5-(3-methylbutanamido)benzoic acid
  • 4-(1-Benzofuran-4-yl)-3-nitrobenzaldehyde
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