5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

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Names

[ CAS No. ]:
103003-96-9

[ Name ]:
5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

[Synonym ]:
N-(4-(1,3-Diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)-L-glutamic acid
5,10-Methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin
L-Glutamic acid,N-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)
Mthdaz

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Molecular Formula ]:
C22H26N6O5

[ Molecular Weight ]:
454.47900

[ Exact Mass ]:
454.19600

[ PSA ]:
186.22000

[ LogP ]:
1.31360

[ Index of Refraction ]:
1.704

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-diethyl 2-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido[5,4-e]indolizin-8-yl)benzamido)pentanedioate
  • H-Glu(OEt)-OEt.HCl
  • methyl 4-amino-4-deoxy-5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazapteroate

DownStream

Related Compounds

  • 2-tert-butyl-6-hydroxy-3,4-dihydro-2H-1-benzopyran-4-one
  • 5-chloro-N-{[4-(morpholin-4-yl)-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-yl]methyl}thiophene-2-sulfonamide
  • Ethyl 2-{[6-(butan-2-yl)pyrimidin-4-yl]amino}acetate
  • N-({5-[hydroxy(phenyl)methyl]thiophen-2-yl}methyl)ethane-1-sulfonamide
  • N-({5-[hydroxy(phenyl)methyl]thiophen-2-yl}methyl)butane-1-sulfonamide
  • N-({5-[hydroxy(phenyl)methyl]thiophen-2-yl}methyl)-1-phenylmethanesulfonamide
  • N-({5-[hydroxy(phenyl)methyl]thiophen-2-yl}methyl)-2-phenylethane-1-sulfonamide
  • 4-[(4-{6-Tert-butyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}piperidin-1-yl)sulfonyl]morpholine
  • 2-(p-Tolyl)-4-((4-(trifluoromethyl)benzyl)sulfonyl)morpholine
  • 1-(3-(Tert-butylsulfonyl)pyrrolidin-1-yl)-2-(4-chlorophenyl)ethanone
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