5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

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Names

[ CAS No. ]:
103003-96-9

[ Name ]:
5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

[Synonym ]:
N-(4-(1,3-Diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)-L-glutamic acid
5,10-Methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin
L-Glutamic acid,N-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)
Mthdaz

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Molecular Formula ]:
C22H26N6O5

[ Molecular Weight ]:
454.47900

[ Exact Mass ]:
454.19600

[ PSA ]:
186.22000

[ LogP ]:
1.31360

[ Index of Refraction ]:
1.704

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-diethyl 2-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido[5,4-e]indolizin-8-yl)benzamido)pentanedioate
  • H-Glu(OEt)-OEt.HCl
  • methyl 4-amino-4-deoxy-5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazapteroate

DownStream

Related Compounds

  • 1-(3-Methylbut-2-en-2-yl)cyclohex-1-ene
  • 3-(Propan-2-yl)hex-1-yne
  • Cyclohexanecarboxamide, 1-(hydroxymethyl)-N-methyl
  • 1-Chloro-7-methylisoquinolin-6-amine
  • 4-Bromo-2-chloro-1-cyclopentylsulfonylbenzene
  • 4-(2-Oxo-propyl)-nicotinic acid
  • (4-Chlorophenyl)(5-cyclopropyl-6-methoxy-2-pyridinyl)methanone
  • (3-methyl-1-oxo-1H-[2,7]naphthyridin-2-yl)-carbamic acid tert-butyl ester
  • N-methyl-N-[2-[methyl(4-nitrobenzoyl)amino]ethyl]carbamic acid 1,1-dimethylethyl ester
  • N-[2-(dimethylamino)ethyl]-N-methyl-4-nitrobenzenesulfonamide
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