5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

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Names

[ CAS No. ]:
103003-96-9

[ Name ]:
5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin

[Synonym ]:
N-(4-(1,3-Diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)-L-glutamic acid
5,10-Methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin
L-Glutamic acid,N-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido(5,4-e)indolizin-8-yl)benzoyl)
Mthdaz

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Molecular Formula ]:
C22H26N6O5

[ Molecular Weight ]:
454.47900

[ Exact Mass ]:
454.19600

[ PSA ]:
186.22000

[ LogP ]:
1.31360

[ Index of Refraction ]:
1.704

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S)-diethyl 2-(4-(1,3-diamino-5,6,6a,7,8,9-hexahydropyrimido[5,4-e]indolizin-8-yl)benzamido)pentanedioate
  • H-Glu(OEt)-OEt.HCl
  • methyl 4-amino-4-deoxy-5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazapteroate

DownStream

Related Compounds

  • (2,4-Dichlorothiazol-5-yl)methanamine
  • 1-(2-Chloro-5-(trifluoromethyl)pyridin-3-yl)ethanol
  • 6-Chloro-3-nitroimidazo[1,2-a]pyridine-2-carbaldehyde
  • Imidazo[1,2-a]pyridine-2-carboxaldehyde, 6-bromo-3-nitro-
  • 1H-Pyrazole-5-carbonitrile, 3-methoxy-1-methyl-
  • 3-Ethoxy-1-methyl-1H-pyrazole-5-methanol
  • 1-(4-Bromo-2-chloro-6-fluorophenyl)ethan-1-ol
  • 5-Bromo-1-chloro-2-(chloromethyl)-3-fluorobenzene
  • (4-Bromo-2-chloro-6-fluorophenyl)methanamine
  • 2-(4-Bromo-2-chloro-6-fluorophenyl)acetonitrile
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