d(+)fructofuranose 1,6-diphosphate tetra(cyclohexylammonium) salt

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Names

[ CAS No. ]:
103213-44-1

[ Name ]:
d(+)fructofuranose 1,6-diphosphate tetra(cyclohexylammonium) salt

[Synonym ]:
D-FRUCTOSE 1,6-DIPHOSPHATE TETRA(CYCLOHEXYLAMMONIUM) SALT
HEXOSE DIPHOSPHATE TETRA(CYCLOHEXYLAMMONIUM) SALT
HARDEN-YOUNG ESTER TETRA(CYCLOHEXYLAMMONIUM) SALT
D-Tagatose-1,6-bisphosphat tetrakis(cyclohexylammonium) Salz
d-fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt
D-FRUCTOSE 1,6-DIPHOSPHATE*TETRA(CYCLOHE XYMAMMONIUM

Chemical & Physical Properties

[ Molecular Formula ]:
C6H26N4O12P2

[ Molecular Weight ]:
408.23800

[ Exact Mass ]:
408.10200

[ PSA ]:
242.22000

[ LogP ]:
0.11440

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • 1,3-Dihydroxyacetone
  • dihydroxyacetone phosphate
  • (2-hydroxy-3-oxopropyl) phosphate

DownStream

  • dihydroxyacetone phosphate
  • (2-hydroxy-3-oxopropyl) phosphate

Articles

Fructose-1,6-bisphosphate attenuates induction of nitric oxide synthase in microglia stimulated with lipopolysaccharide.

Life Sci. 90(9-10) , 365-72, (2011)

Fructose-1,6-bisphosphate (FBP) is a glycolytic intermediate with neuroprotective action in various brain injury models. However, the mechanism underlying the neuroprotection of FBP has not been fully...

Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes.

Handbook of Experimental Pharmacology 203 , 279-301, (2011)

Fructose-1,6-bisphosphatase (FBPase), a rate-controlling enzyme of gluconeogenesis, has emerged as an important target for the treatment of type 2 diabetes due to the well-recognized role of excessive...

Inhibition of fructose 1,6-bisphosphatase reduces excessive endogenous glucose production and attenuates hyperglycemia in Zucker diabetic fatty rats.

Diabetes 55 , 1747-1754, (2006)

Gluconeogenesis is increased in type 2 diabetes and contributes significantly to fasting and postprandial hyperglycemia. We recently reported the discovery of the first potent and selective inhibitors...


More Articles


Related Compounds

  • 4-[[[(4a(2)-Methyl[1,1a(2)-biphenyl]-4-yl)sulfonyl]amino]methyl]benzoic acid
  • 2-[[4-(4-Methylphenyl)phenyl]sulfonylamino]acetic acid
  • 3-{[(3-Methoxyphenyl)sulfonyl]amino}benzoic acid
  • N-[4-(1,3-benzoxazol-2-yl)phenyl]-1-(cyclopropylcarbonyl)prolinamide
  • (2E,6E)-2,6-bis[(1-methyl-1H-indol-3-yl)methylidene]cyclohexan-1-one
  • (2E,5Z)-2-(4-(dimethylamino)benzylidene)-5-(3-ethylbenzo[d]thiazol-2(3H)-ylidene)cyclopentanone
  • 2-(2-(5-Chlorothiophen-2-yl)acetamido)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
  • 1-Cyclopropyl-3-(thiophen-2-yl)-1-(thiophen-3-ylmethyl)urea
  • 1-Cyclopropyl-3-(2-fluorophenyl)-1-(thiophen-3-ylmethyl)urea
  • 1-(2H-1,3-benzodioxol-5-yl)-3-cyclopropyl-3-[(thiophen-3-yl)methyl]urea
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