H-Leu-Leu-Leu-OH

Suppliers

Names

[ CAS No. ]:
10329-75-6

[ Name ]:
H-Leu-Leu-Leu-OH

[Synonym ]:
L-LEUCY-L-LEUCYL-L-LEUCINE
tri-leucine
LEU-LEU-LEU
MFCD00038309
Leucylleucylleucin
Leu-leu-leucrystalline
L-LEUCYL-L-LEUCYL-L-LEUCINE
L-LEUCYLLEUCYLLEUCINE
leucyl-leucyl-leucine
H-LEU-LEU-LEU-OH

Chemical & Physical Properties

[ Density]:
1.057g/cm3

[ Boiling Point ]:
589.6ºC at 760mmHg

[ Molecular Formula ]:
C18H35N3O4

[ Molecular Weight ]:
357.48800

[ Flash Point ]:
310.4ºC

[ Exact Mass ]:
357.26300

[ PSA ]:
121.52000

[ LogP ]:
2.98830

[ Vapour Pressure ]:
1.99E-15mmHg at 25°C

[ Index of Refraction ]:
1.488

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • 2-bromo-4-methylpentanoyl chloride

DownStream

Articles

Inhibition of brain tumor growth by intravenous poly (β-L-malic acid) nanobioconjugate with pH-dependent drug release [corrected].

Proc. Natl. Acad. Sci. U. S. A. 107 , 18143-18148, (2010)

Effective treatment of brain neurological disorders such as Alzheimer's disease, multiple sclerosis, or tumors should be possible with drug delivery through blood-brain barrier (BBB) or blood-brain tu...

Trileucine improves aerosol performance and stability of spray-dried powders for inhalation.

J. Pharm. Sci. 97 , 287-302, (2008)

For particles to be useful medicinal aerosols, not only their aerodynamic diameter has to be on the order of a few micrometers but also they have to be chemically and physically stable. Manufacture of...

Temozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid).

Pharm. Res. 27 , 2317-2329, (2010)

Temozolomide (TMZ) is a pro-drug releasing a DNA alkylating agent that is the most effective drug to treat glial tumors when combined with radiation. TMZ is toxic, and therapeutic dosages are limited ...


More Articles


Related Compounds

  • H-Leu-Leu-Leu-Phe-OMe · HCl
  • H-Leu-Leu-Leu-NH2
  • (2S)-4-methyl-2-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]pentanoic acid
  • (2S)-4-methyl-2-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]amino]pentanoyl]amino]pentanoic acid
  • Leu-Leu
  • H-Leu-Leu-Tyr-OH
  • N-(1-cyclopentanecarbonyl-2,3-dihydro-1H-indol-6-yl)-1-(4-fluorophenyl)methanesulfonamide
  • N-(1-(cyclopentanecarbonyl)indolin-6-yl)-2-(4-methoxyphenyl)ethanesulfonamide
  • N-(1-pivaloylindolin-6-yl)propane-1-sulfonamide
  • N-(4-(N-(1-pivaloylindolin-6-yl)sulfamoyl)phenyl)acetamide
  • N-(1-pivaloylindolin-6-yl)methanesulfonamide
  • N-[1-(2,2-dimethylpropanoyl)-2,3-dihydro-1H-indol-6-yl]-2,5-dimethoxybenzene-1-sulfonamide
  • N-(1-pivaloylindolin-6-yl)thiophene-2-sulfonamide
  • N-[1-(2,2-dimethylpropanoyl)-2,3-dihydro-1H-indol-6-yl]-3,4-dimethoxybenzene-1-sulfonamide
  • 3-chloro-N-(1-pivaloylindolin-6-yl)benzenesulfonamide
  • 2-chloro-N-(1-pivaloylindolin-6-yl)benzenesulfonamide
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