8-DeMethoxy-8-fluoro Gatifloxacin

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Names

[ CAS No. ]:
103460-89-5

[ Name ]:
8-DeMethoxy-8-fluoro Gatifloxacin

[Synonym ]:
AMQ2
3-Quinolinecarboxylic acid, 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-
1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazinyl)-4-oxohydroquinoline-3-carboxylic acid
8-Demethoxy-8-fluoro Gatifloxacin
1-Cyclopropyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
566.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H19F2N3O3

[ Molecular Weight ]:
363.359

[ Flash Point ]:
296.7±30.1 °C

[ Exact Mass ]:
363.139435

[ PSA ]:
74.57000

[ LogP ]:
1.55

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.618

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 2-Methylpiperazine

DownStream

  • Gatifloxacin hydrochloride

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 8-Fluoroisoquinoline
  • 8-Desmethoxy-8-fluoro Moxifloxacin
  • 8-Fluoroquinoline
  • 8-Fluoro-4-cinnolinethiol
  • 8-Fluoro-2-tetralone
  • 8-fluoroquinolin-3-amine
  • ethyl 2-({[4-(1H-tetrazol-1-yl)phenyl]carbonyl}amino)-1,3-thiazole-4-carboxylate
  • N-(1,3-dihydro-2H-benzimidazol-2-ylidene)-3-(4-methoxy-1H-indol-1-yl)propanamide
  • N-[2-(4-chloro-1H-indol-1-yl)ethyl]-2-(4-oxoquinazolin-3(4H)-yl)acetamide
  • 2-(1-oxophthalazin-2(1H)-yl)-N-(1,3-thiazol-2-yl)acetamide
  • 2-{2-[4-(3-methoxyphenyl)piperazino]-2-oxoethyl}-2,5,6,7,8,9-hexahydro-3H-cyclohepta[c]pyridazin-3-one
  • ethyl {2-[(5,6,7,8-tetrahydro-4H-cyclohepta[d][1,2]oxazol-3-ylcarbonyl)amino]-1,3-thiazol-4-yl}acetate
  • 2-{2-[4-(4-chlorophenyl)-4-hydroxypiperidino]-2-oxoethyl}-2,5,6,7,8,9-hexahydro-3H-cyclohepta[c]pyridazin-3-one
  • N-cyclopropyl-3-([1,2,4]triazolo[4,3-b]pyridazin-6-yloxy)benzamide
  • N-(2,4-dimethoxyphenyl)-2-(3-oxo-3,5,6,7,8,9-hexahydro-2H-cyclohepta[c]pyridazin-2-yl)acetamide
  • 4-tert-butyl-N-(2-methyl-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)benzamide
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