8-DeMethoxy-8-fluoro Gatifloxacin

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Names

[ CAS No. ]:
103460-89-5

[ Name ]:
8-DeMethoxy-8-fluoro Gatifloxacin

[Synonym ]:
AMQ2
3-Quinolinecarboxylic acid, 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-
1-Cyclopropyl-6,8-difluoro-7-(3-methylpiperazinyl)-4-oxohydroquinoline-3-carboxylic acid
8-Demethoxy-8-fluoro Gatifloxacin
1-Cyclopropyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
566.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H19F2N3O3

[ Molecular Weight ]:
363.359

[ Flash Point ]:
296.7±30.1 °C

[ Exact Mass ]:
363.139435

[ PSA ]:
74.57000

[ LogP ]:
1.55

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.618

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 2-Methylpiperazine

DownStream

  • Gatifloxacin hydrochloride

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 8-Fluoroisoquinoline
  • 8-Desmethoxy-8-fluoro Moxifloxacin
  • 8-Fluoroquinoline
  • 8-Fluoro-4-cinnolinethiol
  • 8-Fluoro-2-tetralone
  • 8-fluoroquinolin-3-amine
  • 3,7-Dioxa-10-azaspiro[5.6]dodecane
  • N-(2-(furan-3-yl)-2-hydroxyethyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-(2-(furan-3-yl)-2-hydroxyethyl)-[1,1'-biphenyl]-4-carboxamide
  • 3-bromo-N-[2-(furan-3-yl)-2-hydroxyethyl]benzamide
  • 2-bromo-N-[2-(furan-3-yl)-2-hydroxyethyl]benzamide
  • N-(2-(furan-3-yl)-2-hydroxyethyl)-2-(naphthalen-2-yloxy)acetamide
  • N-[2-(furan-3-yl)-2-hydroxyethyl]-2-phenoxybenzamide
  • N-(2-(furan-3-yl)-2-hydroxyethyl)-3-(phenylsulfonyl)propanamide
  • 2-(4-chlorophenoxy)-N-[2-(furan-3-yl)-2-hydroxyethyl]-2-methylpropanamide
  • 2-ethoxy-N-(2-(furan-3-yl)-2-hydroxyethyl)-1-naphthamide
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